Figure 1.

Cumulative incidence of adverse events in patients with and without CTO. Unadjusted cumulative incidence function was used to visualize differences in survival outcomes in patients with CTO (n = 922) and significant CAD without CTO (n = 2,675), coupled with log-rank tests. CTO was associated with higher event rates of all-cause mortality, cardiovascular death, and a MACE, defined as a composite of cardiovascular death/MI/HF hospitalization. The no-CTO group had significant CAD, defined as ≥50% stenosis in ≥1 coronary artery.