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. Author manuscript; available in PMC: 2024 Mar 18.
Published in final edited form as: Biotechnol Bioeng. 2020 Jan 23;117(4):1063–1071. doi: 10.1002/bit.27264

Table 2.

Antibody species from reoxidized samples quantified by fragment analysis.

Antibody Control (Not reduced), % Monomer Reduced, % Monomer Reduced, % New Species Reduced, % Fragment
BisAb-A 95 12 29 59
BisAb-B 96 6 34 60
BisAb-C 98 56 15 29
BisAb-D 94 6 26 68
parental mAb 90 13 10 77

Light chain dimer