Supplementary Table 1. Association between PET parameters and pathological characteristics of ccRCC.
68Ga-PSMA-11 PET/CT | 18F-FDG PET/CT | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SUVmax | Pa value | SUVmean | Pa value | SUVpeak | Pa value | TLR | Pa value | SUVmax | Pa value | SUVmean | Pa value | SUVpeak | Pa value | TLR | Pa value | ||
Tumor necrosis | <0.001 | 0.016 | 0.026 | 0.017 | 0.119 | 0.057 | 0.107 | 0.241 | |||||||||
Negative | 17.39 | 9.01 | 10.72 | 2.17 | 3.97 | 2.51 | 2.95 | 1.26 | |||||||||
7.58-25.20) | (4.04-13.68) | (5.39-18.44) | (1.32-3.93) | (2.98-6.40) | (1.82-3.48) | (2.33-4.95) | (1.04-1.96) | ||||||||||
Positive | 30.51 | 15.39 | 20.79(16.91-23.47) | 4.15 | 5.92 | 3.79 | 4.15 | 1.96 | |||||||||
(26.18-32.54) | (12.58-19.25) | (3.29-4.81) | (3.32-6.81) | (2.57-4.49) | (2.88-5.61) | (1.16-2.06) | |||||||||||
Sarcomatoid or rhabdoid feature | <0.001 | 0.001 | 0.003 | 0.001 | 0.038 | 0.148 | 0.126 | 0.089 | |||||||||
Negative | 18.76 | 10.23 | 13.91 | 2.64 | 4.02 | 2.69 | 3.44 | 1.26 | |||||||||
(8.91-26.93) | (5.06-13.21) | (6.85-19.35) | (1.50-4.03) | (3.03-6.79) | (1.83-4.05) | (2.34-5.38) | (1.04-2.06) | ||||||||||
Positive | 33.93 | 15.67 | 20.80(19.74-22.74) | 4.82 | 6.79 | 3.55 | 4.71 | 1.82 | |||||||||
(32.54-35.33) | (15.39-18.53) | (4.39-4.87) | (5.45-8.04) | (2.56-6.31) | (3.57-7.11) | (1.61-2.50) | |||||||||||
Adverse pathology * | <0.001 | 0.001 | 0.001 | 0.001 | 0.049 | 0.055 | 0.079 | 0.15 | |||||||||
Negative | 14.94 | 8.39 | 9.89 | 2.1 | 3.69 | 2.35 | 2.76 | 1.23 | |||||||||
(7.36-23.32) | (4.02-12.65) | (5.22-23.52) | (1.20-3.39) | (2.94-6.40) | (1.77-3.48) | (2.32-4.95) | (1.04-2.17) | ||||||||||
Positive | 31.55 | 15.48 | 20.79 | 4.3 | 5.59 | 2.99 | 4.44 | 1.68 | |||||||||
(27.87-34.39) | (10.21-15.86) | (18.02-22.74) | (3.51-4.82) | (4.52-6.81) | (2.56-4.49) | (2.95-5.61) | (1.33-2.01) |
Adverse pathology is defined as tumor presenting with necrosis or a sarcomatoid or rhabdoid feature
P values were calculated with Mann-Whitney U test
ccRCC = clear-cell renal cell carcinoma; SUVmax = maximal standard uptake value; SUVmean = mean standard uptake value; SUVpeak = peak standard uptake value; TLR = tumor-to-liver standard uptake value ratio
Data are median (interquartile range) for SUVmax, SUVmean, SUVpeak and TLR