Table 3:

Clinical characteristics and effects on change in six-minute walk distance and maximal treadmill walking time in participants with PAD randomized to supervised treadmill exercise vs. control (continued)

Subgroup	Change in six minute walk distance (meters)				Maximal treadmill walk time (minutes)
	Absolute change		Percentage change		Absolute change		Percentage change
	Absolute change difference, (95% CI)	P value for interaction	Percentage change difference, (95% CI)	P value for interaction	Absolute change difference, (95% CI)	P value for interaction	Percentage change difference, (95% CI)	P value for interaction
Baseline six-minute walk distance (≥334 vs. <334 meters)	−24.0 (−51.4, 3.4)	0.086	−15.0% (−26.5%, −3.5%)	0.011	−0.1 (−1.9, 1.6)	0.88	−38.3% (−84.2%, 7.7%)	0.10
Baseline maximal treadmill walking time (≥6.3 vs. <6.3 minutes)	−5.1 (−33.6, 23.5)	0.73	−4.3% (−16.3%, 7.6%)	0.48	−1.0 (−2.7, 0.7)	0.24	−91.1% (−131.7%, −50.6)	<.001
Adherence to study intervention sessions (≥70% vs. ≤70%)	−15.8 (−45.8, 14.3)	0.30	−2.9% (−15.7%, 9.8%)	0.65	1.4 (−0.4, 3.3)	0.14	9.4% (−40.0%, 58.8%)	0.71

^*Data shown represent changes in six-minute walk distance or treadmill walking time in participants randomized to exercise relative to the control group by subgroup. For example, in the first row of data, participants age 67 and older randomized to supervised exercise therapy gained 10.3 meters less and 4.8% less on the six-minute walk test relative to control compared to participants less than age 67. However, these differences between those age 67 and older vs. those less than age 67 were not statistically significant, since the p value for interaction was not < 0.05.