Table 4.
Change in six-minute walk distance within groups of participants randomized to exercise and control, respectively
| N | Baseline six-minute walk, mean (STD) | 6-month six-minute walk, mean (STD) | Within group change in six-minute walk distance, mean (95% CI) | Between group change in six-minute walk distance, mean (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Age | ||||||
| Participants randomized to exercise | ||||||
| ≤ 67 years | 64 | 345.84 (98.83) | 379.52 (90.67) | 33.69 (18.69, 48.68) | Reference | 0.2154 |
| > 67 years | 77 | 329.63 (92.91) | 350.54 (86.54) | 20.91 (7.23, 34.58) | −12.78 (−33.07, 7.52) | |
| Participants randomized to control | ||||||
| ≤ 67 years | 78 | 356.42 (85.57) | 348.18 (102.30) | −8.24 (−21.87, 5.39) | Reference | 0.9427 |
| > 67 years | 64 | 310.84 (95.24) | 301.87 (94.66) | −8.98 (−24.02, 6.07) | −0.74 (−21.04, 19.56) | |
| Sex | ||||||
| Participants randomized to exercise | ||||||
| Female | 63 | 336.95 (91.52) | 351.71 (86.96) | 14.76 (−0.20, 29.72) | Reference | 0.0355 |
| Male | 78 | 337.01 (99.44) | 373.37 (90.54) | 36.36 (22.92, 49.81) | 21.60 (1.49, 41.72) | |
| Participants randomized to control | ||||||
| Female | 59 | 301.72 (83.88) | 289.27 (94.33) | −12.46 (−28.10, 3.20) | Reference | 0.5225 |
| Male | 83 | 360.16 (91.22) | 354.34 (97.76) | −5.81 (−19.01, 7.38) | 6.64 (−13.83, 27.10) | |
| Race | ||||||
| Participants randomized to exercise | ||||||
| Not African American | 61 | 349.32 (91.40) | 373.48 (87.92) | 24.17 (8.73, 39.61) | Reference | 0.6667 |
| African American | 80 | 327.58 (98.28) | 356.23 (90.17) | 28.64 (15.16, 42.12) | 4.47 (−16.02, 24.97) | |
| Participants randomized to control | ||||||
| Not African American | 52 | 331.12 (104.54) | 319.61 (118.14) | −11.52 (−28.20, 5.16) | Reference | 0.6615 |
| African American | 90 | 338.62 (85.39) | 331.75 (90.51) | −6.87 (−19.55, 5.81) | 4.65 (−16.30, 25.60) | |
| ABI | ||||||
| Participants randomized to exercise | ||||||
| ≤ 0.65 | 76 | 303.09 (80.29) | 336.46 (75.07) | 33.36 (19.62, 47.11) | Reference | 0.1607 |
| > 0.65 | 65 | 376.62 (97.45) | 395.54 (94.49) | 18.93 (4.07, 33.79) | −14.44 (−34.68, 5.80) | |
| Participants randomized to control | ||||||
| ≤ 0.65 | 66 | 313.48 (84.31) | 309.45 (91.50) | −4.03 (−18.81, 10.75) | Reference | 0.4075 |
| > 0.65 | 76 | 355.33 (95.52) | 342.81 (107.22) | −12.52 (−26.29, 1.26) | −8.49 (−28.69, 11.71) | |
| BMI | ||||||
| Participants randomized to exercise | ||||||
| ≤ 30 kg/m2 | 64 | 359.93 (92.15) | 384.13 (82.80) | 24.20 (9.13, 39.27) | Reference | 0.6567 |
| > 30 kg/m2 | 77 | 317.91 (94.86) | 346.71 (91.44) | 28.79 (15.05, 42.53) | 4.60 (−15.80, 24.99) | |
| Participants randomized to control | ||||||
| ≤ 30 kg/m2 | 74 | 359.99 (88.60) | 349.56 (100.67) | −10.42 (−24.41, 3.56) | Reference | 0.7054 |
| > 30 kg/m2 | 68 | 309.64 (90.22) | 303.09 (96.92) | −6.55 (−21.14, 8.04) | 3.87 (−16.34, 24.08) | |
| Current smoker | ||||||
| Participants randomized to exercise | ||||||
| No | 96 | 341.06 (101.56) | 365.49 (92.59) | 24.43 (12.13, 36.72) | Reference | 0.5176 |
| Yes | 45 | 328.29 (81.99) | 359.86 (82.71) | 31.57 (13.61, 49.53) | 7.14 (−14.62, 28.91) | |
| Participants randomized to control | ||||||
| No | 103 | 326.90 (92.82) | 322.79 (102.68) | −4.11 (−15.88, 7.67) | Reference | 0.1549 |
| Yes | 39 | 359.59 (88.74) | 339.23 (97.71) | −20.36 (−39.49, −1.22) | −16.25 (−38.72, 6.22) | |