Table 4.
Associations of clinical characteristics with change in six-minute walk among participants randomized to exercise and control, respectively (continued)
| N | Baseline six-minute walk, mean (STD) | 6-month six-minute walk, mean (STD) | Change of six-minute walk within group, mean (95% CI) | Change of six-minute walk between groups, mean (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Diabetes | ||||||
| Participants randomized to exercise | ||||||
| No | 90 | 344.64 (95.69) | 369.88 (90.96) | 25.24 (12.53, 37.95) | Reference | 0.7043 |
| Yes | 51 | 323.48 (94.98) | 352.78 (86.08) | 29.30 (12.42, 46.19) | 4.07 (−17.07, 25.20) | |
| Participants randomized to control | ||||||
| No | 87 | 345.48 (91.75) | 340.77 (103.27) | −4.71 (−17.57, 8.16) | Reference | 0.3414 |
| Yes | 55 | 320.69 (92.66) | 306.01 (95.05) | −14.69 (−30.86, 1.49) | −9.98 (−30.65, 10.69) | |
| Coronary artery disease | ||||||
| Participants randomized to exercise | ||||||
| No | 97 | 348.03 (95.13) | 377.05 (80.97) | 29.02 (16.79, 41.25) | Reference | 0.5042 |
| Yes | 44 | 312.65 (93.27) | 334.25 (100.18) | 21.61 (3.45, 37.77) | −7.42 (−29.31, 14.48) | |
| Participants randomized to control | ||||||
| No | 106 | 338.60 (91.89) | 327.44 (101.38) | −11.15 (−22.81, 0.51) | Reference | 0.3858 |
| Yes | 36 | 327.86 (95.40) | 326.90 (102.35) | −0.97 (−20.97, 19.04) | 10.19 (−12.97, 33.35) | |
| Pulmonary disease | ||||||
| Participants randomized to exercise | ||||||
| No | 128 | 340.13 (94.78) | 364.15 (88.77) | 24.02 (13.46, 34.59) | Reference | 0.1003 |
| Yes | 13 | 306.07 (102.45) | 359.20 (98.00) | 53.13 (19.99, 86.27) | 29.10 (−5.68, 63.89) | |
| Participants randomized to control | ||||||
| No | 122 | 339.19 (95.47) | 329.47 (105.63) | −9.72 (−20.68, 1.23) | Reference | 0.6458 |
| Yes | 18 | 315.01 (73.40) | 312.40 (72.68) | −2.61 (−31.12, 25.91) | 7.12 (−23.43, 37.66) | |
| Heart failure | ||||||
| Participants randomized to exercise | ||||||
| No | 129 | 336.88 (95.07) | 364.46 (89.73) | 27.58 (16.98, 38.18) | Reference | 0.2952 |
| Yes | 10 | 364.54 (95.46) | 371.12 (86.85) | 6.58 (−31.49, 44.65) | −21.00 (−60.52, 18.52) | |
| Participants randomized to control | ||||||
| No | 122 | 340.26 (94.36) | 328.99 (104.40) | −11.27 (−22.10, −0.44) | Reference | 0.1910 |
| Yes | 20 | 309.11 (77.51) | 317.02 (80.93) | 7.91 (−18.84, 34.66) | 19.18 (−9.68, 48.04) | |
| Symptoms of classic intermittent claudication | ||||||
| Participants randomized to exercise | ||||||
| No | 90 | 335.65 (96.76) | 364.28 (87.69) | 28.63 (15.92, 41.34) | Reference | 0.6196 |
| Yes | 51 | 339.34 (94.54) | 362.66 (92.94) | 23.31 (6.43, 40.19) | −5.32 (−26.45, 15.81) | |
| Participants randomized to control | ||||||
| No | 98 | 337.71 (95.71) | 327.62 (105.07) | −10.09 (−22.24, 2.06) | Reference | 0.6584 |
| Yes | 44 | 331.80 (86.08) | 326.61 (93.38) | −5.20 (−23.33, 12.94) | 4.89 (−16.94, 26.72) | |
| Asymptomatic (no exertional leg symptoms) | ||||||
| Participants randomized to exercise | ||||||
| No | 133 | 333.81 (94.36) | 361.64 (88.79) | 27.83 (17.40, 38.26) | Reference | 0.3741 |
| Yes | 8 | 389.72 (108.00) | 397.80 (96.95) | 8.08 (−34.46, 50.62) | −19.75 (−63.55, 24.05) | |
| Participants randomized to control | ||||||
| No | 136 | 334.68 (93.15) | 326.90 (102.42) | −7.78 (−18.08, 2.52) | Reference | 0.4597 |
| Yes | 6 | 362.97 (80.33) | 336.40 (76.34) | −26.57 (−75.61, 22.47) | −18.79 (−68.90, 31.32) | |