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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Clin Pharmacol Ther. 2023 Dec 18;115(3):452–456. doi: 10.1002/cpt.3131

Table 1:

Clinical and Genetic Information for Patients Included in the Analysis (n=201)

N (%)
Sex Male 143 (71.1%)
Female 58 (28.9%)
Self-reported Race Caucasian 196 (97.5%)
Asian 2 (1.0%)
Black 1 (0.5%)
American Indian/Pacific Islander 1 (0.5%)
Unknown/Not Reported 1 (0.5%)
Indication Actinic Keratosis 159 (79.1%)
Verruca 22 (9.14%)
Warts 10 (5.0%)
Other 10 (5.0%)
DPYD Genotype DPYD*1/*1 (Wild-type) 187 (93.0%)
DPYD*1/*2A (AS=1.0) 3 (1.5%)
DPYD*1/*13 (AS=1.0) 0
DPYD*1/p.D949V (AS=1.5) 1 (0.5%)
DPYD*1/HapB3 (AS=1.5) 10 (5.0%)
DPYD*1/p.Y186C (AS=1.5) 0
Total variant carriers 14 (7.0%)
Observed Toxicity Grade 1+ Dermatological Toxicity 22 (10.9%)
Grade 3+ 0 (0%)