Skip to main content
. Author manuscript; available in PMC: 2024 Dec 19.
Published in final edited form as: ACS Synth Biol. 2024 Jan 9;13(1):337–350. doi: 10.1021/acssynbio.3c00597

Figure 4. Discovery of lasso peptides from Mycetohabitans sp. B13.

Figure 4.

(A) Graphical representation of the mycetolassin BGC (NZ_FTPM01000001). Genes mlsA1 and mlsA2 encode for the precursor peptides of mycetolassin-15 and mycetolassin-18, respectively. (B) HPLC traces of culture extracts showing production of two lasso peptides. Detection at 210 nm. (C) Sequences and predicted structures of mycetolassin-15 (1) and mycetolassin-18 (2). (D) MALDI-TOF mass spectrometry showing detection of the two expected m/z features for [M+H]+.