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. Author manuscript; available in PMC: 2024 Mar 18.
Published in final edited form as: Birth Defects Res. 2020 Sep 30;113(2):144–151. doi: 10.1002/bdr2.1811

TABLE 2.

Birth defects among infants with and without NAS in Delaware, 2010–2017

Exposure/outcome Birth defect No birth defect Total cORb (95% CI) aORc (95% CI)
NASa 56 (3.4%) 1,595 (96.6%) 1,651 1.0 (0.8–1.3) 0.9 (0.6–1.1)
Non-NAS 2,728 (3.4%) 76,908 (96.6%) 79,636
Total 2,784 (3.4%) 78,503 (96.6%) 81,287

Abbreviations: aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; cOR, crude odds ratio; NAS, neonatal abstinence syndrome.

a

NAS measured using ICD-9-CM/ICD-10-CM codes 779.5 and P96.1.

b

cOR with 95% CI.

c

aOR with 95% CI. Adjusted a priori for plurality, maternal age, maternal education, maternal race/ethnicity, insurance status at delivery, county of residence, trimester of prenatal care initiation, cigarette use during pregnancy, and pre-pregnancy BMI.