Table 4.
Imaging characteristics of intracerebral hemorrhage.
| IP-IVH | P-IPH | p Value | |
|---|---|---|---|
| CT-based imaging characteristics | (n = 46) | (n = 1230) | |
| Hemorrhage volume, mean ± SD (mm3) | 54.6 (±51.8) | 44.2 (±51.3) | 0.482 |
| Modified Graeb score, median (IQR) | 5 (3, 8) | ||
| IVH near lobar regions | 28 (61) | ||
| MRI-based imaging characteristics | (n = 35) | (n = 750) | |
| Presence of cerebral microinfarcts | 6 (16) | 97 (13) | 0.614 |
| Severe white matter hyperintensities (Fazekas ≥ 2) | 32 (87) | 584 (77) | 0.228 |
| White matter hyperintensity patterns | |||
| Multiple subcortical spots | 8 (22) | 81 (11) | 0.057 |
| Anterior subcortical patches | 10 (27) | 114 (15) | 0.062 |
| Large posterior subcortical patches | 13 (35) | 198 (26) | 0.254 |
| Peri-basal ganglia pattern | 2 (5) | 57 (8) | 0.628 |
| Presence of lacunes | 18 (49) | 253 (34) | 0.075 |
| Presence of deep lacunes | 15 (41) | 220 (29) | 0.143 |
| Presence of lobar lacunes | 5 (14) | 73 (10) | 0.399 |
| Presence of severe perivascular spaces (BG) | 7 (19) | 82 (11) | 0.175 |
| Presence of severe perivascular spaces (CSO) | 5 (14) | 69 (9) | 0.380 |
| Presence of cortical superficial siderosis | 7 (20) | 121 (16) | 0.489 |
| Presence of cerebral microbleeds | 18 (51) | 424 (57) | 0.603 |
| Presence of cerebral microbleeds (deep) | 8 (23) | 193 (26) | 0.844 |
| Presence of cerebral microbleeds (lobar) | 14 (40) | 344 (46) | 0.603 |
| Strictly deep ICH/microbleeds | 4 (11) | 58 (7) | 0.349 |
| Strictly lobar ICH/microbleeds | 10 (29) | 209 (28) | 0.928 |
| Mixed-location ICH/microbleeds | 4 (11) | 135 (18) | 0.495 |
| No microbleeds | 17 (49) | 348 (46) | 0.863 |
| Presence of any cSVD biomarker | 33 (94) | 667 (89) | 0.415 |
| SVD score, median (IQR) | 2 (1, 3) | 2 (1, 3) | 0.066 |
| Etiologic classification | |||
| Undetermined | 15 (43) | 188 (25) | 0.028 |
| Hypertensive cerebral small vessel disease | 8 (23) | 209 (28) | 0.517 |
| Possible cerebral amyloid angiopathy | 2 (6) | 148 (20) | 0.045 |
| Probable cerebral amyloid angiopathy | 10 (29) | 205 (27) | 0.848 |
| Cerebral amyloid angiopathy (total) | 12 (34) | 353 (47) | 0.166 |
Data are counts (n) and percentages (%), means and standard deviations (SD), or medians and interquartile ranges (IQR).
CT: computed tomography; MRI: magnetic resonance imaging; IVH: idiopathic primary intraventricular hemorrhage; P-IPH: intraparenchymal hemorrhage; BG: basal ganglia; CSO: centrum semiovale; ICH: intracerebral hemorrhage; cSVD: cerebral small vessel disease.