Table 2.

Imaging Characteristics of DOAC Users With and Without ICH

	ICH free (n = 94)	ICH (n = 48)	p Value
Severe white matter hyperintensities (Fazekas score > 1)	49 (52)	38 (79)	< 0.01
Lacunes	28 (30)	22 (46)	0.06
Severe enlarged perivascular spaces (EPVS)	11 (12)	7 (15)	0.59
Basal ganglia EPVS	5 (5)	5 (11)	0.30
Centrum semiovale EPVS	6 (6)	3 (6)	1.00
Cortical superficial siderosis	1 (1)	11 (23)	< 0.01
Cerebral microbleeds	22 (23)	29 (60)	< 0.01
Any one small vessel disease biomarker	62 (66)	47 (98)	< 0.01
Small vessel disease score	1 (0, 2)	2 (1, 3)	< 0.01
Probable cerebral amyloid angiopathy	4 (4)	16 (33)	< 0.01

Data are counts (n) and percentages (%), means and standard deviations (SD), or medians and interquartile ranges (IQR)

DOAC direct oral anticoagulant, ICH intracerebral hemorrhage