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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: Am J Hematol. 2024 Jan 21;99(4):523–533. doi: 10.1002/ajh.27207

Table 2A.

MPSS score definition on the basis of the training cohort

Risks β OS HR (95% CI) p Score assigned

Thrombocytopenia 0.471 1.60 (1.24–2.08) <0.001 2
Elevated LDH 0.347 1.41 (1.09–1.84) 0.01 1
ISS III 0.556 1.74 (1.41–2.16) <0.001 2
0 HRA Reference 0
1 HRA 0.399 1.49 (1.17–1.90) 0.001 1
≥2 HRA 0.846 2.33 (1.76–3.10) <0.001 2