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. 2023 Dec 22;20(3):1815–1826. doi: 10.1002/alz.13571

TABLE 2.

Logistic regression models of visual rating scales.

Model 1: Sex effects Abnormal score, n (%)
Effect OR SE 95% CI P Males Females
GCA‐F Sex 2.121 0.260 [1.284, 3.566] 0.004 81 (39.71%) 34 (27.64%)
MTA Sex 0.804 0.234 [0.508, 1.273] 0.350 74 (36.27%) 51 (41.46%)
PA Sex 1.459 0.237 [0.917, 2.325] 0.111 128 (62.75%) 68 (55.28%)
Model 2: Sex‐by‐age interaction Age of abnormal score, mean (SD)
Effect OR SE 95% CI P Males Females
GCA‐F Sex×age 1.018 0.034 [0.951, 1.087] 0.590 74.68 (6.66) 77.06 (7.05)
MTA Sex×age 1.028 0.036 [0.956, 1.103] 0.451 73.43 (6.20) 77.11 (6.72)
PA Sex×age 0.977 0.029 [0.922, 1.034] 0.417 72.45 (8.48) 75.93 (8.24)

Note: Model 1 is a binary logistic regression model with visual rating scale scores as the dependent variable (normal vs abnormal) and both sex (variable of interest) and age (control variable) as the independent variables. For the MTA scale, the model included age‐adjusted score as the dependent variable (normal vs abnormal) and sex (variable of interest). Model 2 is a binary logistic regression model with visual rating scale scores as the dependent variable (normal vs abnormal) and the interaction between sex and age (variable of interest), together with sex and age as the independent variables. For visual rating scales, values “0” and “1” correspond to “normal” and “abnormal” scores according to established cutoffs. For sex, values “0” and “1” correspond to male and female sex, respectively. Statistically significant effects are shown in bold (P ≤ 0.05).

Abbreviations: GCA‐F, global cortical atrophy‐frontal subscale; MTA, medial temporal atrophy scale; PA, posterior atrophy scale.