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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: J Clin Virol. 2024 Jan 9;171:105639. doi: 10.1016/j.jcv.2024.105639

Table 2.

Predicted drug resistance by portable Nanopore sequencing.

Specimen Predicted drug resistancea Linked cross-resistanceb ART
EM2045 NNRTI: EFV (h), NVP (h)
INSTI: BIC (i), CAB (i), DTG (i), EVG (i), RAL (l)
3: NNRTI: EFV (h), NVP (h) and INSTI: BIC (i), CAB (i), DTG (i), EVG (i), RAL (l)
5: NNRTI: EFV (h), NVP (h) and INSTI: BIC (l), CAB (l), DTG (l), EVG (l), RAL (p)
NRTI: FTC and TAF
INSTI: BIC and DTG
NNRTI: EFV (h) and NVP (h)
INSTI: BIC (l), CAB (i), DTG (i), EVG (i), RAL (i)
3: NNRTI: EFV (h), NVP (h) and INSTI: BIC (l), CAB (i), DTG (i), EVG (i), RAL (i)
2: NNRTI: EFV (h), NVP (h) and INSTI: BIC (l), CAB (l), DTG (l), EVG (l), RAL (p)
KI6633 NRTI: ABC (l), 3TC (p), D4T (l), DDI (l), FTC (p), TDF (l)
NNRTI: ETR (p), RPV (l)
2: NRTI: ABC (l), 3TC (p), D4T (l), DDI (l), FTC (p), TDF (l)
5: NNRTI: ETR (p), RPV (l)
PI: ATV
NRTI: 3TC, FTC, TDF, ZDV (AZT)
NNRTI: EFV
ZI9923 NNRTI: ETR (p), RPV (l) 29: NNRTI: ETR (p), RPV (l) PI: DRV RTV
NRTI: FTC, TDF
NNRTI: ETR (p), RPV (l) 10: NNRTI: ETR (p), RPV (l)
MP7985 NRTI: AZT (i), D4T (l), DDI (p) 1: NRTI: AZT (i), D4T (l), DDI (p) NRTI: 3TC, ABC, ZDV
none none
701010222-1 INSTI: EVG (p), RAL (p) 6: INSTI: EVG (p), RAL (p) naive
INSTI: EVG (p), RAL (p) 10: INSTI: EVG (p), RAL (p)
701010222-2 INSTI: EVG (p), RAL (p) 3: INSTI: EVG (p), RAL (p) naive
703010863-2 NRTI: 3TC (h), DDI (p), FTC (h), ABC (l)
NNRTI: NVP (h), EFV (h)
1: NRTI: 3TC (h), DDI (p), FTC (h), ABC (l) and NNRTI: NVP (h), EFV (h) naive
NRTI: 3TC (h), DDI (p), FTC (h), ABC (l)
NNRTI: NVP (h), EFV (h)
9: NRTI: 3TC (h), DDI (p), FTC (h), ABC (l) and NNRTI: NVP (h), EFV (h)
703011231-2 INSTI: EVG (p), RAL (p) 10: INSTI: EVG (p), RAL (p) naive
a

The resistance levels are denoted by high-level resistance (h), intermediate-level resistance (i), low-level resistance (l), and potential low-level resistance (p).

b

Number of consensus sequences with a particular linkage is presented.