TABLE 2.
Neutralization of primary isolates of HIV-1 in MT-2 cells and human PBMC by sera from HIV-1-infected individuals
| Seruma | Neutralizing antibody
titer inb:
|
||||
|---|---|---|---|---|---|
| MT-2
cells
|
MT-2 cells/PBMC
|
||||
| IIIB | MN | V89872 | V67970 | H69172 | |
| T84468 | 248 | 2,241 | <5/<5 | <5/<5 | <5/<5 |
| Y44003 | 21 | 3,149 | <5/<5 | 6/<5 | <5/<5 |
| W05477 | 191 | 670 | <5/<5 | 79/25 | <5/<5 |
| V97490 | 97 | 336 | <5/5 | 12/<5 | 6/<5 |
| AA4875 | 165 | 763 | <5/<5 | 14/5 | <5/<5 |
a
Sera are from HIV-1-infected individuals.
b
Titers measured in MT-2 cells are the reciprocal serum dilutions at which 50% of cells were protected from virus-induced cell killing; titers measured in PBMC are the reciprocal serum dilutions that reduced p24 synthesis by >80%.