TABLE 3.

Associations between each reproductive history factor with MCI (n = 2092) in Study of Latinos‐Investigation of Neurocognitive Aging.

	Model 1	Model 2	Model 3
	OR [95% CI]	OR [95% CI]	OR [95% CI]
Female hormone use
No	Ref	Ref	Ref
Yes	0.29 * [0.11;0.76]	0.34 * [0.13;0.91]	0.35 * [0.13;0.94]
Contraceptive use
No	Ref	Ref	Ref
Yes	0.77 [0.52;1.12]	0.85 [0.57;1.25]	0.81 [0.53;1.23]
Age at menarche	1.01 [0.91;1.11]	0.98 [0.89;1.08]	0.99 [0.90;1.09]
Number of live births	1.08 [0.99;1.19]	1.02 [0.92;1.12]	1.00 [0.91;1.11]
Number of pregnancies	1.04 [0.97;1.12]	1.01 [0.94;1.08]	0.99 [0.92;1.07]
Age at menopause	1.00 [0.96;1.03]	0.99 [0.96;1.03]	1.00 [0.97;1.03]
Menopause age (>45 years)
≤45 years	Ref	Ref	Ref
>45 years	1.19 [0.81;1.75]	1.24 [0.85;1.83]	1.29 [0.87;1.91]
Reproductive span	0.99 [0.96;1.03]	0.99 [0.96;1.03]	1.00 [0.96;1.03]

Note: Sample size is unweighted; all other reported values are weighted to represent the target population.

Each reproductive history factor was entered separately into model. Model 1 was crude, Model 2 was adjusted for age and education, Model 3 was adjusted for Model 2 + language, Hispanic/Latino heritage, field center, income, marital status, insurance status, nativity, and body mass index.

Abbreviations: CI, confidence interval; M#, model; MCI, mild cognitive impairment; OR, odds ratio.

^* p < .05.