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. 2024 Feb 29;12:1336845. doi: 10.3389/fpubh.2024.1336845

Table 5.

Univariate and multivariate logistic regression analysis of clinical and genomic factors associated with HIV late presentation (LP).

Univariate and multivariate logistic regression analysis of clinical and genomic factors associated with HIV late presenter (LP) status
Unadjusted Adjusted (N = 325)
OR (95% CI) p-value OR (95% CI) p-value
Clinical
Age at diagnosis (groups)
18–24 1 1
25–34 1.18 (0.66–2.14) 0.58 1.09 (0.54–2.23) 0.8
35–44 2.69 (1.44–5.13) 0.002 2.67 (1.28–5.7) 0.01
45–54 4.91 (2.12–12) < 0.001 4.11 (1.49–12.1) 0.008
≥55 1.93 (0.57–6.42) 0.28 4.18 (1–18.6) 0.053
Viral load (copies/mL)
≤10,000 1 1
10,000–100,000 3.06 (1.41–7.39) 0.007 12.9 (3.54–84.2) < 0.001
≥100,000 9.62 (4.46–23.3) < 0.001 33.6 (9.14–220) < 0.001
HLA-B57
Negative 1
Positive 0.36 (0.05–1.47) 0.2
Genomic
Any SDRM
No 1
Yes 1.29 (0.58–2.85) 0.53
Subtype
B 1 1
A1 1.15 (0.57–2.27) 0.69 1.57 (0.7–3.51) 0.3
C 2.20 (0.83–6.22) 0.12 1.76 (0.54–6.05) 0.4
Other 0.84 (0.43–1.6) 0.60 0.66 (0.31–1.37) 0.3
Recombinant 0.93 (0.39–2.16) 0.88 0.95 (0.35–2.55) >0.9
B vs. non-B
B 1
Non-B 1.08 (0.69–1.69) 0.73
Ambiguity rate 1.73 (1.25–2.5) 0.002 1.52 (1.09–2.24) 0.024
Recentness
Chronic 1
Recent 0.26 (0.17–0.42) < 0.001

STI, Sexual transmitted infections.