Table 2.
Sensitivity and specificity of each test compared to modeled gold standard using 4-test and 6-test latent class analysis
| 4 tests: RDT, blood smear, PCR, HRP-2 antigenemia | 6 tests: RDT, blood smear, PCR, HRP-2 antigenemia, long and short half-life antibody | |||
|---|---|---|---|---|
| Test | sensitivity | specificity | sensitivity | specificity |
| Blood smear | 93.59 (89.44–97.74) |
99.63 (98.28–100.00) |
93.61 (89.46–97.77) |
98.48 (95.79–100.00) |
| PET | 99.87 (99.25–100.00) |
93.43 (87.88–98.98) |
99.86 (99.18–100.00) |
92.21 (86.27–98.15) |
| RDT +, HRP-2 + | 98.37 (96.21–100.00) |
-- | -- | -- |
| RDT −, HRP-2 − | -- | 45.47 (34.77–6.17) |
-- | -- |
| RDT | -- | -- | 99.10 (97.43–100.00) |
93.33 (87.83–98.83) |
| HRP-2 | -- | -- | 99.91 (99.33–100.00) |
47.27 (36.60–57.93) |
| Antibodies: long +, short + | 87.26 (81.71–92.82) |
-- | ||
| Antibodies: long −, short − | -- | 15.47 (07.75–23.19) |
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