Performance of relevant catalyst systems in the model reaction of 1a and 2 using anisole and butyl acetate as solvents.
| Entry | Catalyst | [mol%] | Conv. [%], 1 h in Anisole | Conv. [%], 1 h, in nBuOAc | ||
|---|---|---|---|---|---|---|
| 1a a | 2 b | 1a a | 2 b | |||
| 1 | 7/GCc | 0.33/1 | 51 | 52 | 66 | 63 |
| 2 | FeCl3/DMAP | 1/1 | 30 | 30 | 41 | 43 |
| 3 | TBAB | 2 | 19 | 17 | 26 | 27 |
| 4 | Et3NBn | 2 | 19 | 20 | 24 | 27 |
| 5 | PPh3 | 2 | 20 | 19 | 16 | 11 |
| 6 | PPh4Br | 2 | 47 | 52 | 55 | 53 |