Table 2.
Univariable and Multivariable Logistic Regression Analysis for Missed Adjuvant Therapy Among 26,953 Patients With a Documented Indication for Adjuvant Radiation or Adjuvant Chemoradiation
| Logistic Regression for Missed Adjuvant Therapy (n = 26,953) | ||||
|---|---|---|---|---|
| Univariable |
Multivariable |
|||
| OR (95% CI) | p value | OR (95% CI) | p value | |
|
| ||||
| Age | 1.04 (1.03–1.04) | <.001 | 1.04 (1.04–1.04) | <.001 |
| Male | 0.81 (0.76–0.85) | <.001 | 0.94 (0.89–1.01) | .079 |
| Race | ||||
| Non-Hispanic white | [Reference] | NA | [Reference] | NA |
| Hispanic | 0.78 (0.68–0.89) | <.001 | 0.80 (0.68–0.93) | .004 |
| Black | 0.81 (0.73–0.90) | <.001 | 0.87 (0.76–0.97) | .019 |
| Asian-Pacific Islander | 0.65 (0.56–0.75) | <.001 | 0.71 (0.60–0.83) | <.001 |
| Other-unknown | 0.89 (0.74–1.08) | .24 | 0.86 (0.68–1.07) | .171 |
| Insurance | ||||
| Private | [Reference] | NA | [Reference] | NA |
| Medicare-Medicaid-other government | 1.72 (1.62–1.82) | <.001 | 1.06 (0.99–1.14) | .116 |
| Uninsured | 1.08 (0.94–1.24) | .249 | 1.09 (0.94–1.27) | .235 |
| Unknown | 1.80 (1.46–2.23) | <.001 | 1.5 (1.18–1.90) | .001 |
| Median income | ||||
| <$38,000 | [Reference] | NA | [Reference] | NA |
| $38,000–$47,999 | 0.99 (0.92–1.09) | .945 | 0.96 (0.87–1.05) | .366 |
| $48,000–$62,999 | 0.98 (0.91–1.07) | .646 | 0.98 (0.89–1.08) | .672 |
| $63,000 | 0.85 (0.78–0.92) | <.001 | 0.87 (0.79–0.96) | .007 |
| No high-school diploma (%) | ||||
| ≥21 | [Reference] | NA | ||
| 13.0%-20.9 | 1.01 (0.93–1.10) | .876 | ||
| 7.0%-12.9 | 0.95 (0.87–1.03) | .204 | ||
| <7.0 | 0.93 (0.85–1.02) | .134 | ||
| Setting | ||||
| Metropolitan | [Reference] | NA | [Reference] | NA |
| Urban | 1.13 (1.05–1.21) | <.001 | 0.9 (0.82–0.99) | .026 |
| Rural | 1.13 (0.94–1.37) | .194 | 0.82 (0.66–1.02) | .076 |
| Charlson comorbidity score | ||||
| 0 | [Reference] | NA | [Reference] | NA |
| 1 | 1.26 (1.18–1.35) | <.001 | 1.15 (1.06–1.24) | <.001 |
| 2 | 1.57 (1.40–1.77) | <.001 | 1.33 (1.16–1.51) | <.001 |
| 3+ | 2.06 (1.78–2.39) | <.001 | 1.81 (1.53–2.14) | <.001 |
| Distance from treatment center | ||||
| ≤50 miles | [Reference] | NA | [Reference] | NA |
| >50 miles | 1.60 (1.50–1.70) | <.001 | 1.54 (1.42–1.67) | <.001 |
| Primary site | ||||
| Tongue | [Reference] | NA | [Reference] | NA |
| Floor of mouth | 1.09 (1.01–1.18) | .026 | 1.02 (0.93–1.11) | .724 |
| Gum | 1.51 (1.40–1.63) | <.001 | 1.01 (0.93–1.11) | .764 |
| Hard palate | 1.32 (1.12–1.55) | <.001 | 0.91 (0.75–1.10) | .325 |
| Lip | 2.51 (2.14–2.94) | <.001 | 2.3 (1.92–2.75) | <.001 |
| Other | 1.12 (1.04–1.21) | .003 | 0.9 (0.82–0.98) | .015 |
| Facility type | ||||
| Nonacademic | [Reference] | NA | [Reference] | NA |
| Academic | 1.36 (1.29–1.44) | <.001 | 1.37 (1.29–1.47) | <.001 |
Abbreviations: CI, confidence interval; OR, odds ratio.