Table 1.
Demographic, metabolic characteristics and PANSS scores of first-episode drug-naïve schizophrenia patients.
| Schizophrenia (n = 143) | groups | t | p | ||
|---|---|---|---|---|---|
| normal/under weight(n = 95) | overweight/obesity (n = 48) | ||||
| Age (years) | 25.73 ± 7.31 | 24.94 ± 7.05 | 27.31 ± 7.64 | t = -1.850 | 0.066 |
| Years of Education | 13.07 ± 2.72 | 12.89 ± 2.93 | 13.42 ± 2.26 | t = -1.178 | 0.241 |
| IQ | 107.90 ± 11.70 | 107.92 ± 11.83 | 107.86 ± 11.58 | t = 0.029 | 0.977 |
| DUI (months) | 11.29 ± 8.18 | 10.93 ± 8.10 | 12.00 ± 8.38 | t = -0.740 | 0.461 |
| BMI (kg/m2) | 22.75 ± 4.01 | 20.42 ± 1.96 | 27.35 ± 2.87 | t = -17.010 | <0.001*** |
| FBG (mmol/L) | 4.51 ± 0.56 | 4.51 ± 0.57 | 4.51 ± 0.55 | t = 0.017 | 0.986 |
| TG (mmol/L) | 1.15 ± 0.79 | 0.98 ± 0.61 | 1.50 ± 1.00 | t = -3.292 | 0.002** |
| TC (mmol/L) | 4.06 ± 0.88 | 3.97 ± 0.74 | 4.23 ± 1.09 | t = -1.490 | 0.141 |
| LDL-C (mmol/L) | 2.29 ± 0.74 | 2.17 ± 0.63 | 2.51 ± 0.88 | t = -2.388 | 0.020* |
| HDL-C (mmol/L) | 1.15 ± 0.25 | 1.23 ± 0.23 | 1.00 ± 0.22 | t = 5.660 | <0.001*** |
| PANSS | |||||
| Positive symptom | 23.76 ± 3.59 | 23.48 ± 3.75 | 24.29 ± 3.22 | t = -1.274 | 0.205 |
| Negative symptom | 19.35 ± 3.85 | 19.36 ± 3.95 | 19.33 ± 3.67 | t = 0.036 | 0.971 |
| General psychopathology | 45.24 ± 3.44 | 45.01 ± 3.38 | 45.69 ± 3.54 | t = -1.112 | 0.268 |
| Total symptom | 88.30 ± 7.25 | 87.85 ± 7.28 | 89.19 ± 7.170 | t = -1.041 | 0.300 |
Means ± SD value, *p < 0.05, **p < 0.01, ***p < 0.001.
IQ, intelligence quotient; DUI, duration of illness; BMI, body mass index; FBG, fasting blood glucose; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; PANSS, Positive and Negative Syndrome Scale.