Table 3.
Results of multiple linear regression analysis of main fetal growth parameters among live born singletons.
| Q1 | Q2 | Q3 | Q4 | ||||
|---|---|---|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | β (95% CI) | P value | ||
| Mid-term ultrasound measurements | |||||||
| Biparietal diameter | 0.00(-0.01,0.01) | 0.364 | Reference | -0.01(-0.02,-0.00) | 0.004 | -0.03(-0.04,-0.02) | <0.001 |
| Humerus length | 0.00(-0.00,0.01) | 0.803 | Reference | -0.02(-0.02,-0.01) | <0.001 | -0.03(-0.03,-0.02) | <0.001 |
| Femur length | 0.00(-0.00,0.01) | 0.335 | Reference | -0.02(-0.02,-0.01) | <0.001 | -0.03(-0.04,-0.02) | <0.001 |
| Head circumference | -0.00(-0.03,0.02) | 0.813 | Reference | -0.02(-0.05,0.01) | 0.140 | -0.08(-0.11,-0.05) | <0.001 |
| Abdominal circumference | 0.03(-0.00,0.06) | 0.079 | Reference | -0.05(-0.08,-0.02) | 0.001 | -0.14(-0.17,-0.11) | <0.001 |
| Estimated fetal weight | 1.41(-0.37,3.20) | 0.119 | Reference | -4.18(-5.97,-2.39) | <0.001 | -9.36(-11.23,-7.49) | <0.001 |
| Neonatal outcomes | |||||||
| Gestational age | 0.01(-0.03,0.05) | 0.592 | Reference | -0.00(-0.04,0.03) | 0.909 | -0.03(-0.07,0.00) | 0.082 |
| Body length | 0.04(0.01,0.08) | 0.024 | Reference | -0.01(-0.05,0.03) | 0.630 | -0.06(-0.10,-0.02) | 0.006 |
| Birthweight | 9.12(-2.72,20.96) | 0.131 | Reference | -17.32(-29.23,-5.41) | 0.004 | -36.89(-49.32,-24.45) | <0.001 |
| Birthweight z-score | 0.03(0.00,-0.06) | 0.023 | Reference | -0.04(-0.06,-0.01) | 0.004 | -0.09(-0.11,-0.06) | <0.001 |
Analyses were adjusted for age, BMI, gravidity, parity, educational level, alcohol and cigarette consumption before pregnancy, ALT, AST, gestational age at sampling, pregnancy induced hypertension and gestational diabetes mellitus.