Figure 5.

Inhibitor binding. (A) LUMIER data and model fit for TRY-GL3 binding. The shaded region indicates the confidence interval. (B) CPC-GL3 data and model fit. (C) Competition of GL1 with TRY, for different ratios indicated in legend. (D) Competition of GL1 with TRY (red) and CPC (blue), using a model that includes binding between the inhibitors and GL1. The yellow data indicates the GL1-GL3 binding in absence of TRY/CPC. (E, F) show the prediction of percentages of complexes formed using the estimates from the data for GL1 competition with TRY and CPC, respectively.