Table 3.
Subacute and chronic phase univariable Cox Regression Analysis of MACE
| Subacute phase | Chronic phase | |||
|---|---|---|---|---|
| Hazard Ratio (95% CI) | p value | Hazard Ratio (95% CI) | p value | |
| Baseline characteristics | ||||
| Age | 1 (0.97, 1.03) | 0.82 | 1 (0.97, 1.03) | 0.93 |
| Male sex | 0.77 (0.3, 1.99) | 0.59 | 0.76 (0.3, 1.98) | 0.58 |
| Body mass index | 0.9 (0.79, 1.03) | 0.12 | 0.93 (0.82, 1.05) | 0.24 |
| Hypertension | 1.27 (0.65, 2.5) | 0.49 | 1.27 (0.65, 2.5) | 0.49 |
| Dyslipidemia | 1.08 (0.47, 2.47) | 0.87 | 1.08 (0.47, 2.48) | 0.86 |
| Diabetes mellitus | 1.33 (0.68, 2.62) | 0.41 | 1.33 (0.68, 2.62) | 0.41 |
| Anterior infarction | 1.42 (0.62, 3.25) | 0.40 | 1.41 (0.62, 3.23) | 0.41 |
| Pain-to-balloon time (h) | 1 (1, 1.01) | 0.11 | 1 (1, 1.01) | 0.11 |
| NYHA class > 3 | 1.57 (1.38, 4.46) | < 0.001 | 19.57 (4.38, 87.46) | < 0.001 |
| Pre-pPCI TIMI flow < 3 | 1.81 (0.75, 4.37) | 0.19 | 1.81 (0.75, 4.38) | 0.19 |
| Post-pPCI TIMI flow < 3 | 3.89 (1.61, 9.42) | 0.003 | 4.15 (1.71, 10.1) | 0.002 |
| CMR parameters | ||||
| Heart rate | 1.03 (1.01, 1.06) | 0.02 | 1.02 (1, 1.05) | 0.08 |
| LVEF | 0.96 (0.94, 0.99) | 0.005 | 0.98 (0.97, 1) | 0.009 |
| LVMi | 1.02 (1, 1.04) | 0.049 | 1.03 (1, 1.05) | 0.03 |
| LVEDVi | 1.03 (1.01, 1.04) | < 0.001 | 1.03 (1.02, 1.04) | < 0.001 |
| LVESVi | 1.03 (1.02, 1.04) | < 0.001 | 1.03 (1.02, 1.04) | < 0.001 |
| LVSVi | 1 (0.97, 1.04) | 0.82 | 0.99 (0.96, 1.02) | 0.611 |
| Infarct size, per 10% | 2.21 (1.65, 2.97) | < 0.001 | 2.14 (1.6, 2.87) | < 0.001 |
| Infarct transmural extent, per 10% | 1.19 (0.97, 1.45) | 0.10 | 1.16 (0.96, 1.4) | 0.13 |
| LV thrombus | 0.44 (0.06, 3.21) | 0.42 | 0.82 (0.11, 5.97) | 0.84 |
| LV aneurysm | 1.27 (0.58, 2.79) | 0.55 | 1.38 (0.65, 2.94) | 0.40 |
| MVO/IMH | 1.61 (0.84, 3.1) | 0.15 | 0.93 (0.46, 1.88) | 0.83 |
| Papillary infarction | 0.56 (0.20, 1.57) | 0.27 | 0.56 (0.20, 1.58) | 0.27 |
| FD measures, per 1% | ||||
| Global FD | 0.89 (0.82, 0.96) | 0.005 | 0.93 (0.86, 1) | 0.04 |
| Infarct area FD | 0.95 (0.9, 1) | 0.07 | 0.95 (0.9, 1) | 0.04 |
| Remote area FD | 0.95 (0.9, 1) | 0.04 | 0.96 (0.91, 1.01) | 0.13 |
| ΔGlobal FD | 0.85 (0.79, 0.91) | < 0.001 | 0.92 (0.86, 0.98) | 0.007 |
| ΔInfarct area FD | 0.95 (0.88, 1.03) | 0.23 | 0.96 (0.9, 1.02) | 0.17 |
| ΔRemote area FD | 0.9 (0.84, 0.98) | 0.01 | 0.96 (0.89, 1.02) | 0.21 |
TIMI Thrombolysis in myocardial infarction, LVEF Left ventricular ejection fraction, LVEDVi Left ventricular end-diastolic volume index, LVESVi Left ventricular end-systolic volume index, LVMi Left ventricular mass index, LVSVi Left ventricular stroke volume index, MVO Microvascular obstruction, IMH Intramyocardial hemorrhage, LVT Left ventricular thrombus, FD Fractal dimension