Table 1.

Clinico-radiological and pathologic features of various gastric SMTs

	Schwannoma	Leiomyoma	GIST
Age	40-50 years	50-70 years	60-65 years
Gender	Female >Male	Male =Female	Male >Female
Site	Lesser curvature >body >antrum >fundus	Cardia >GE junction	Greater curvature
Radiological Features (CECT Scan)	Hypodense, well- demarcated lesion with homogenous enhancement. Exophytic or mixed growth pattern. No haemorrhage, necrosis, cystic change or calcification.	Homogenous hypodense lesion with mild-moderate contrast enhancement. Endoluminal growth pattern.	Large, hyper-vascular lesions with heterogenous contrast enhancement. Predominantly exophytic growth pattern. Haemorrhage, necrosis and cystic change.
Histopathology	Encapsulated tumours consisting of spindle cells with prominent lymphoid aggregations. Antoni-A, Antoni-B areas Absence of typical Verocay bodies.	Spindle cells with eosinophilic cytoplasm	Cellular morphology ranges from spindle shaped to epitheloid in character. 70% spindle- cell type, 20% epitheloid cell type, 10%-mixed type.
IHC	Positive for S100, GFAP, Vimentin, Calretinin, SOX-10, PGP9.5	Positive for Desmin, SMA	Positive for CD-117, CD-34, Actin
Malignant Transformation	Extremely rare	Extremely rare	20-30%
Treatment	Surgery	Surgery	Surgery + TKI

GIST: gastrointestinal stromal tumor, CECT: contrast enhanced computed tomography, IHC: immunohistochemistry, TKI: Tyrosine kinase inhibitor