Table 2.
TUG parameters in controls, iRBD and PD
| CP (65) | iRBD (23) | PD (60) | P-value* | iRBD-CP difference | PD-CP difference | PD-iRBD difference | |
|---|---|---|---|---|---|---|---|
| TUG NORMAL SPEED | |||||||
| TUG duration (s) | 11.3 ± 2.09 | 12.8 ± 1.8 | 14.0 ± 3.5 | <0.001b § | 1.4 ± 0.8 | 2.4±0.5 | 1 ± 0.8 |
| Duration Of Turns (s) | 2.3 ± 0.4 | 2.8 ± 0.4 | 3.0 ± 0.6 | <0.001a § | 0.5 ± 0.1 | 0.7±0.1 | 0.2 ± 0.1 |
| Mean Angular Velocity (°/s) | 82 ± 14 | 67 ± 8 | 61 ± 15 | <0.001a *§ | −15.0 ± 3.4 | −20.4±2.4 | −5.4 ± 3 |
| Peak Angular Velocity (°/s) | 194 ± 34 | 152 ± 22 | 138 ± 28 | <0.001a *§ | −41.9 ± 7.7 | −54.0±5.5 | −12.1 ± 7.5 |
| TUG FAST SPEED | |||||||
| TUG duration (s) | 8.9 ± 1.8 | 9.2 ± 0.9 | 10.9 ± 2.4 | <0.001b §# | 0.3 ± 0.6 | 1.8±0.4 | 1.5 ± 0.5 |
| % Variation TUG duration | −21.8 ± 8.8 | -27.7 ± 6.4 | -20.3 ± 6.7 | 0.011b *# | |||
| Duration Of Turns (s) | 1.9 ± 0.3 | 2.2 ± 0.4 | 2.5 ± 0.5 | <0.001b §# | 0.3 ± 0.1 | 0.6±0.1 | 0.3 ± 0.1 |
| % Variation Turning duration | −16.6 ± 12.6 | −21.22 ± 12.3 | −13.8 ± 10.2 | 0.042a | |||
| Mean Angular Velocity (°/s) | 98 ± 18 | 85 ± 15 | 72 ± 16 | <0.001a §# | −12.9 ± 4.2 | −24.4±2.9 | −11.5 ± 4.1 |
| %VariationMeanVelocity | 20.9 ± 16.4 | 26.1 ± 18.4 | 16.8 ± 13.2 | 0.219b | |||
| Peak Angular Velocity (°/s) | 235 ± 40 | 203 ± 37 | 172 ± 35 | <0.001a §# | −32 ± 9.4 | −62.8 ± 6.7 | −30.8 ± 9.2 |
| %VariationPeakVelocity | 22.6 ± 13.2 | 30.9 ± 20.3 | 22.9 ± 14.8 | 0.822b | |||
Pairwise with Bonferroni Correction for 3 comparisons (*iRBD vs CP; §PD vs CP; #iRBD vs PD). p-value < 0.006 was considered as statistically significant for digital extracted variables.
aParametric comparison corrected for age and sex
bNon-parametric comparison corrected for age and sex
CP control participants, iRBD subjects with idiopatic REM sleep behavior disorders, PD Parkinson’s disease patients, TUG timed up and go test.