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. 2024 Mar 18;14:6441. doi: 10.1038/s41598-024-56283-z

Table 3.

The comparison of hemodynamics, analgesia nociception index, bispectral index, and effect-site concentrations of propofol and remifentanil between successful and failure patients during skull pin fixation.

Successful Unsuccessful P value
N 15 11
HR 71.1 ± 11.8 69 ± 13.4 0.683
MAP 97.6 ± 15.5 108.6 ± 15.8 0.101
ANIi 51.1 ± 16.9 27.2 ± 7.9  < 0.001*
BIS 44.9 ± 5.8 47.5 ± 7.4 0.359
Ce of propofol 2.4 ± 0.6 2.2 ± 0.7 0.298
Ce of remifentanil 4.5 ± 0.6 3.8 ± 0.5 0.004*

Ce indicates effect-site concentration; ANIi indicates an instantaneous value calculated as a mobile mean of ANI over 64 s of monitoring.

BIS bispectral index.