Fig. 1. Histogram of age and scanner distributions in the Generation R cohort.

Mean age visit 1: 7.9 years (range = [6.1–10.7], n = 974 [510 male, 464 female]), mean age visit 2: 10.1 years (range = [8.6–12.0], n = 3785 [1879 male, 1906 female]), and mean age visit 3: 14.0 years (range = [12.6–17.1], n = 2511 [1202 male, 1309 female]). 2734 (56.2%) individuals were measured once, 1848 (38.0%) individuals twice, and scans in all three measurement waves were acquired from 280 (5.8%) individuals. Source data are provided as a Source Data file.