Table 2.
Summary of histological results of rat thyroid tissue at study termination expressed as the number of rats with pathological findings per total number of rats examined (incidence and %) per treatment group.
| Incidence | Number of animals observed | Follicular hypertrophy | Follicular hyperplasia | Follicular dilation | No visible lesions |
|---|---|---|---|---|---|
| Control negative | 6 | 0 | 0 | 4 (67%) | 2 (33%) |
| Phenobarbital 500 ppm | 5 | 5 (100%)* | 5 (100%)* | 5 (100%) | 0 |
| Cyproconazole 1000 ppm | 5 | 5 (100%)* | 4 (80%)* | 5 (100%) | 0 |
| Epoxiconazole 900 ppm | 5 | 5 (100%)* | 5 (100%)* | 5 (100%) | 0 |
| Prochloraz 1000 ppm | 4 | 4 (100%)* | 4 (100%)* | 4 (100%) | 0 |
*(p ≤ 0.05), Fisher’s Exact Test.