Table 2. Clinical characteristics and hormonal profile of infertile patients according to birth weight.
| LBW | NBW | HBW | p-valuea | ||
|---|---|---|---|---|---|
| No. of patients (n=1,063) | 79 (7.5) | 807 (76.0) | 177 (16.5) | ||
| Age (y) | 0.6 | ||||
| Median (IQR) | 36 (34–41) | 36 (35–40) | 36 (34–41) | ||
| Range | 22–55 | 18–54 | 20–55 | ||
| BMI (kg/m2) | <0.001 | ||||
| Median (IQR) | 24.4 (22.1–26.7) | 25.2 (23.7–27.3) | 26.1 (23.2–28.1)b | ||
| Range | 18.8–40.0 | 19.1–45.0 | 18.1–41.2 | ||
| CCI ≥1 | 14 (17.7) | 72 (8.9)b | 20 (11.2)b | <0.01 | |
| Current smoking status | 23 (29.1) | 227 (28.1) | 53 (29.9) | 0.2 | |
| Testis volume (prader estimation) | <0.001 | ||||
| Median (IQR) | 15 (11–20) | 18 (12–20)b | 20 (13–25)b | ||
| Range | 3–25 | 2–25 | 7–25 | ||
| Partner’s age (y) | 0.5 | ||||
| Median (IQR) | 34 (31–40) | 34 (30–37) | 34 (30–38) | ||
| Range | 21–48 | 19–48 | 20–47 | ||
| Duration of infertility (mo) | 0.6 | ||||
| Median (IQR) | 18 (12–29) | 18 (12–29) | 18 (12–30) | ||
| Range | 12–55 | 12–60 | 12–60 | ||
| Varicocele (n=535) | 39 (49.4) | 406 (50.3) | 90 (50.8) | 0.7 | |
| FSH (mUI/mL) | 0.01 | ||||
| Median (IQR) | 8.5 (3.3–14.4) | 5.4 (3.5–11.0)b | 5.7 (3.3–9.2)b | ||
| Range | 0.1–57.0 | 0.7–83.7 | 0.1–45.1 | ||
| LH (mUI/mL) | 0.5 | ||||
| Median (IQR) | 4.3 (2.8–6.3) | 4.1 (2.9–6.0) | 4.2 (3.0–5.2) | ||
| Range | 0.3–26.0 | 0.1–56.0 | 0.1–19.2 | ||
| InhB (pg/mL) | 0.06 | ||||
| Median (IQR) | 95.2 (43.3–155.8) | 109.3 (48.8–170.1) | 110.6 (50.7–155.4) | ||
| Range | 6.0–244.7 | 6.8–790.0 | 6.5–291.3 | ||
| tT (ng/mL) | 0.01 | ||||
| Median (IQR) | 4.1 (3.3–5.7) | 4.8 (3.5–5.8)b | 4.9 (3.2–5.6)b | ||
| Range | 1.8–10.7 | 0.9–51.8 | 1.2–9.9 | ||
| E2 (pg/mL) | 0.01 | ||||
| Median (IQR) | 24.0 (21.1–32.5) | 27.4 (24.5–39.2)b | 24.5 (19.8–34.4) | ||
| Range | 5.0–94.0 | 2.2–139.0 | 5.2–84.1 | ||
| SHBG (nmol/L) | 0.9 | ||||
| Median (IQR) | 34 (24–42) | 32 (26–42) | 34 (23–41) | ||
| Range | 15.0–74.0 | 6.0–90 | 10.0–85.0 | ||
| Prolactin (ng/mL) | 0.6 | ||||
| Median (IQR) | 8.8 (6.5–11.8) | 8.5 (6.2–12.1) | 8.3 (6.4–11.2) | ||
| Range | 3.7–19.8 | 1.0–17.0 | 2.5–17.0 | ||
Values are presented as number (%) otherwise indicated.
IQR: interquartile range, LBW: low birth weight, NBW: normal birth weight, HBW: high birth weight, BMI: body mass index, CCI: Charlson Comorbidity Index, FSH: follicle-stimulating hormone, LH: luteinizing hormone, InhB: Inhibin B, tT: total testosterone, E2: estradiol, SHBG: sex hormone-binding globulin.
ap-value according to chi-square test or the Kruskall–Wallis test, as indicated; bp<0.01 vs LBW group.