Table 4. Logistic regression models predicting pathologic SDF index and negative ART outcomes.
| SDF >30% | Negative ART outcomes | |||||||
|---|---|---|---|---|---|---|---|---|
| UVA model | MVA model | UVA model | MVA model | |||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | 95% CI | p-value | 95% CI | p-value | |
| Age | 1.12 (0.84–1.34) | 0.2 | 1.11 (0.81–1.36) | 0.3 | 1.16 (1.02–3.54) | 0.02 | 1.20 (1.08–4.02) | 0.02 |
| LBW | 4.18 (1.82–6.83) | 0.001 | 3.72 (1.91–7.49) | <0.001 | 3.21 (1.24–9.87) | 0.01 | 2.29 (1.13–8.84) | <0.001 |
| CCI≥1 | 1.01 (0.91–1.11) | 0.6 | 1.02 (0.89–1.24) | 0.7 | 1.01 (0.76–1.32) | 0.7 | 1.01 (0.54–1.32) | 0.7 |
| FSH | 2.36 (1.16–4.45) | <0.001 | 1.85 (1.11–5.34) | <0.001 | 1.11 (0.91–1.98) | 0.3 | 1.10 (0.95–2.09) | 0.5 |
| Testicular volume | -0.37 (-0.82–0.85) | 0.1 | -0.48 (-0.84–1.09) | 0.2 | -0.56 (-0.67–1.07) | 0.7 | -0.77 (-0.94–1.15) | 0.9 |
| Varicocele | 1.01 (0.93–1.13) | 0.4 | ||||||
| SDF >30% | – | – | 3.32 (2.09–9.45) | 0.001 | 2.99 (2.10–10.19) | <0.001 | ||
| Partner’s age | 1.35 (1.15–4.76) | 0.001 | 1.34 (1.12–5.02) | 0.001 | ||||
UVA: univariante, MVA: multivariante, ART: assisted reproductive technology, LBW: low birth weight, CCI: Charlson Comorbidity Index, FSH: follicle-stimulating hormone, SDF: sperm DNA fragmentation.