Table 4.

Preoperative and Postoperative Knee Injury and Osteoarthritis Outcome Subscale Scores: Pain, Symptoms, Activities of Daily Living (ADL), Sport and Recreation Function (Sports), and Knee-Related Quality of Life (QOL)

	Treatment Group
	AMUC Group					PRP Group					Control Group
Time Point	Pain	Symptoms	ADL	Sports	QOL	Pain	Symptoms	ADL	Sports	QOL	Pain	Symptoms	ADL	Sports	QOL
Baseline	46.0 ± 23.2	49.8 ± 16.9	51.7 ± 25.5	31.3 ± 25.1	27.4 ± 20.6	51.4 ± 17.6	49.4 ± 21.1	61.6 ± 24.7	46.0 ± 26.6	25.8 ± 16.2	53.0 ± 20.2	60.1 ± 19.3	59.0 ± 22.6	44.8 ± 31.3	31.3 ± 25.3
3 months	70.9 ± 18.3	69.3 ± 16.0	78.8 ± 18.3	58.2 ± 26.9	47.1 ± 26.0	75.3 ± 22.1	71.2 ± 23.8	79.7 ± 25.9	68.9 ± 27.0	49.5 ± 30.1	66.6 ± 19.2	69.2 ± 18.8	68.5 ± 23.1	46.0 ± 33.1	42.1 ± 25.2
	0.0008	0.0011	0.0005	0.0055	0.0208	0.0044	0.0156	0.0802	0.0410	0.0355	0.0017	0.0289	0.0554	0.8626	0.0469
6 months	77.4 ± 15.7	74.5 ± 21.4	81.3 ± 13.9	57.1 ± 25.5	51.8 ± 31.2	68.9 ± 25.5	67.5 ± 25.8	73.1 ± 20.9	45.0 ± 38.6	22.9 ± 17.1	65.6 ± 24.4	69.2 ± 19.3	69.7 ± 24.9	53.2 ± 35.0	43.8 ± 31.3
	0.0010	0.0219	0.0008	0.0405	0.0899	0.0814	0.0860	0.2663	0.9513	0.7569	0.0242	0.0533	0.0665	0.3085	0.0763
12 months	Low n	Low n	Low n	Low n	Low n	55.6 ± 7.3	51.2 ± 7.4	55.4 ± 16.4	60.0 ± 13.2	33.3 ± 20.1	66.9 ± 27.6	69.3 ± 21.8	69.3 ± 27.6	56.5 ± 30.4	53.1 ± 28.1
						0.5668	0.8154	0.6329	0.2560	0.5998	0.1403	0.2449	0.2952	0.2941	0.0264

Notes: Data are presented as mean ± SD. The term Low n indicates inadequate sample size. For the Knee Injury and Osteoarthritis Outcome subscale scores, higher scores indicate better outcomes. P values reflect the statistical significance of the change from baseline.

AMUC, amniotic umbilical cord tissue; PRP, platelet-rich plasma.