Table IV.

Effects of focused-extracorporeal shock wave therapy on inflammatory marker in people with knee osteoarthritis and bone mineral density

Variable	Group A Median (IQR)	Group B	Group C	Group D	Overall	p-value
CRP concentration (μg/mL)  Baseline  Post-intervention  Follow-up	3.931 (3.491) 5.190 (14.218) 4.410 (14.019)	1.125 (1.761) 2.595 (2.810) 8.213 (27.617)	2.850 (3.022) 3.136 (1.735) 5.684 (6.376)	5.341 (8.674) 3.667 (24.765) 3.239 (2.994)	3.039 (3.805) 3.425 (2.922) 4.736 (6.471)	0.2
TNF-α concentration (ng/mL)  Baseline  Post-intervention  Follow-up	0 (4.211) 0 (3.633) 0 (2.176)	2 (0.058) 0 (0.028) 0 (0.023)	0 (0.012) 0.017 (0.035) 0 (0.006)	0 (0.010) 0 (0.040) 0 (0.000)	0 (0.011) 0 (0.035) 0 (0.006)	0.09*
IL-1β concentration (ug/mL)  Baseline  Post-intervention  Follow-up	0.001 (0.300) 0.003 (0.011) 0.020 (0.055)	0.013 (0.584) 0.026 (0.043) 0.019 (0.040)	0.023 (0.037) 0.017 (0.003) 0.020 (0.012)	0.538 (0.757) 0.570 (0.795) 0.447 (0.421)	0.026 (0.178) 0.018 (0.217) 0.020 (0.046)	0.4
IL-6 concentration (pg/mL)  Baseline  Post-intervention  Follow-up	2.270 (11.548) 1.928 (21.822) 2.050 (10.822)	1.820 (2.337) 1.945 (2.163) 1.858 (2.164)	1.694 (12.635) 5.350 (7.048) 1.961 (10.440)	5.124 (13.020) 8.306 (11.408) 4.039 (3.204)	2.303 (7.489) 2.163 (7.048) 2.050 (3.782)	1.0

^*Denote statistical significance (p<0.05).

IQR: interquartile range; CRP: C-reactive protein; TNF-α: tumour necrosis factor; IL-1β: interleukin 1; IL-6: interleukin 6.