Table 3.
Global disability-adjusted life-years per 100 000 people by five broad age categories for all conditions with neurological health loss
| Aged <5 years | Rank | Aged 5–19 years | Rank | Aged 20–59 years | Rank | Aged 60–79 years | Rank | Aged ≥80 years | Rank | |
|---|---|---|---|---|---|---|---|---|---|---|
| All neurological conditions | 11 806·6 (10 144·1–13 813·9) | NA | 1705·4 (1227·4–2372·8) | NA | 3443·1 (2639·2–4531·4) | NA | 13 742·8 (12 096·7–15 569·1) | NA | 38 329·3 (31 687·1–50 519·4) | NA |
| Alzheimer's disease and other dementias | 0·0 (0·0–0·0) | NA | 0·0 (0·0–0·0) | NA | 44·2 (21·2–101·5) | 13 | 1504·2 (746·6–3345·6) | 2 | 13 047·1 (5903·4–27 898·8) | 2 |
| Attention deficit hyperactivity disorder | 2·4 (1·2–4·2) | 24 | 28·3 (14·5–48) | 14 | 10·7 (5·8–17·1) | 23 | 1·0 (0·5–1·9) | 29 | 0·0 (0·0–0·0) | 33 |
| Autism spectrum disorder | 169·1 (114·9–237·3) | 7 | 161·4 (109·2–227·2) | 4 | 146·2 (99·4–206·3) | 6 | 112·9 (77·4–157·1) | 9 | 59·5 (40·5–83·6) | 14 |
| Cerebral malaria | 2·8 (2·0–3·6) | 23 | 8·8 (6·4–11·2) | 22 | 5·0 (3·6–6·3) | 27 | 0·8 (0·6–1·0) | 30 | 0·0 (0·0–0·0) | 32 |
| Congenital birth defects* | 27·2 (15·4–46·4) | 14 | 20·5 (9·4–39·1) | 15 | 17·4 (7·9–33·5) | 19 | 13·1 (5·8–25·5) | 23 | 10·0 (4·3–19·5) | 20 |
| Congenital Zika syndrome* | 0·0 (0·0–0·0) | 30 | 0·0 (0·0–0·0) | NA | 0·0 (0·0–0·0) | NA | 0·0 (0·0–0·0) | NA | 0·0 (0·0–0·0) | NA |
| COVID-19* | 8·6 (0·5–35·7) | 18 | 15·4 (1·0–65·3) | 18 | 40·1 (1·0–133·9) | 16 | 32·6 (0·9–97·5) | 18 | 30·0 (0·9–79·2) | 17 |
| Cystic echinococcosis* | 0·0 (0·0–0·0) | 31 | 0·0 (0·0–0·1) | 34 | 0·1 (0·0–0·1) | 35 | 0·1 (0·1–0·1) | 35 | 0·0 (0·0–0·1) | 31 |
| Diabetic neuropathy | 0·0 (0·0–0·0) | 32 | 1·5 (0·8–2·4) | 27 | 260·5 (171·9–387·6) | 3 | 1397·3 (911·8–1930·8) | 3 | 1493·5 (1026·5–2052·6) | 4 |
| Down syndrome* | 3·2 (2·1–4·7) | 22 | 3·0 (2·0–4·3) | 25 | 1·3 (0·8–1·8) | 31 | 0·1 (0·1–0·2) | 34 | 0·0 (0·0–0·0) | NA |
| Encephalitis | 270·6 (196·3–342·6) | 4 | 49·6 (41·3–59·1) | 11 | 34·9 (30·5–41·0) | 17 | 63·8 (56–73·9) | 14 | 89·6 (74·4–107·0) | 10 |
| Epilepsy | 211·5 (163·7–268·9) | 6 | 185·1 (137·0–261·7) | 3 | 174·0 (134·1–219·5) | 4 | 176·9 (125·9–247·7) | 7 | 268·5 (186·4–379·7) | 5 |
| Fetal alcohol syndrome | 0·4 (0·2–0·7) | 27 | 0·4 (0·2–0·6) | 32 | 0·3 (0·2–0·4) | 34 | 0·1 (0·1–0·2) | 33 | 0·1 (0·1–0·2) | 30 |
| Guillain–Barré syndrome | 0·4 (0·2–0·7) | 28 | 0·5 (0·2–0·8) | 31 | 0·6 (0·3–0·9) | 33 | 1·2 (0·7–2·0) | 28 | 1·4 (0·8–2·2) | 25 |
| Idiopathic intellectual disability | 68·3 (32·4–118·0) | 11 | 70·4 (33·7–118·7) | 7 | 43·1 (19·4–74·0) | 14 | 17·1 (7·2–30·4) | 21 | 9·8 (4·9–16·7) | 21 |
| Klinefelter syndrome* | 0·1 (0·1–0·2) | 29 | 0·0 (0·0–0·1) | 33 | 0·0 (0·0–0·0) | 36 | 0·0 (0·0–0·0) | 36 | 0·0 (0·0–0·0) | 34 |
| Meningitis | 1234·9 (869·5–1741·7) | 2 | 130·4 (111·0–161·3) | 5 | 72·4 (65·0–83·4) | 11 | 69·8 (64·2–77·9) | 13 | 84·1 (75·1–92·4) | 11 |
| Migraine | 0·0 (0·0–0·0) | NA | 380·0 (24·7–946·6) | 1 | 750·8 (117·3–1617·8) | 2 | 451·6 (112·3–953·6) | 4 | 238·3 (65·8–499·5) | 6 |
| Motor neuron disease | 6·2 (4·9–7·7) | 19 | 1·3 (1·0–1·5) | 28 | 8·7 (8·0–9·6) | 24 | 57·3 (53·2–61·9) | 15 | 48·2 (39·8–54·1) | 16 |
| Multiple sclerosis | 0·0 (0·0–0·0) | NA | 0·5 (0·4–0·7) | 30 | 15·1 (12·7–17·8) | 22 | 31·8 (28·1–35·8) | 19 | 24·4 (20·7–28·3) | 18 |
| Neonatal encephalopathy | 8316·7 (7072·6–9991·8) | 1 | 64·9 (46·3–85·6) | 8 | 55·4 (40·1–72·0) | 12 | 25·8 (18·8–33·0) | 20 | 2·1 (1·3–3·0) | 23 |
| Neonatal jaundice* | 13·2 (9·5–16·8) | 15 | 11·6 (8·4–14·8) | 21 | 8·7 (6·3–11·2) | 25 | 3·9 (2·8–5·0) | 26 | 0·4 (0·3–0·6) | 28 |
| Neonatal sepsis* | 42·3 (27·1–61·1) | 13 | 39·5 (24·7–57·1) | 12 | 31·3 (19·6–45·2) | 18 | 13·5 (8·3–19·3) | 22 | 0·6 (0·3–0·9) | 27 |
| Nervous system cancer | 94·9 (71·4–121·5) | 10 | 60·2 (50·3–71·7) | 10 | 106·6 (91·2–125·6) | 7 | 280·0 (245·7–316·1) | 6 | 208·8 (174·3–232·0) | 8 |
| Neural tube defects | 722·6 (580·8–899·4) | 3 | 17·0 (12·5–23·6) | 17 | 4·5 (3·6–5·9) | 29 | 1·6 (1·2–2·1) | 27 | 1·3 (0·9–1·8) | 26 |
| Neurocysticercosis | 0·8 (0·1–1·9) | 25 | 1·6 (0·8–2·5) | 26 | 16·1 (9·1–23·8) | 21 | 45·7 (24·8–76·2) | 17 | 65·4 (36·1–105·0) | 13 |
| Neurosyphilis | 0·7 (0·4–1·0) | 26 | 1·1 (0·7–1·6) | 29 | 0·8 (0·5–1·1) | 32 | 0·6 (0·4–0·8) | 31 | 0·4 (0·3–0·6) | 29 |
| Chromosomal anomalies* | 12·2 (8·1–17·3) | 17 | 5·8 (3·9–8·2) | 24 | 2·3 (1·5–3·3) | 30 | 0·4 (0·2–0·5) | 32 | 0·0 (0·0–0·0) | 36 |
| Other neurological disorders | 44·6 (36·2–54·4) | 12 | 60·2 (44·2–84·0) | 9 | 41·8 (34·6–49·6) | 15 | 94·7 (84·0–106·8) | 11 | 157·8 (133·9–176·9) | 9 |
| Parkinson's disease | 0·0 (0·0–0·0) | NA | 0·0 (0·0–0·0) | NA | 16·2 (13·6–19·1) | 20 | 430·7 (389·5–472·1) | 5 | 1773·2 (1550·8–1925·0) | 3 |
| Preterm birth* | 264·9 (190·4–344·9) | 5 | 234·3 (168·4–305·2) | 2 | 165·7 (120·5–212·9) | 5 | 56·0 (41·9–71·4) | 16 | 14·1 (9·6–20·9) | 19 |
| Rabies | 12·8 (4·5–24·6) | 16 | 12·3 (6·6–17·9) | 19 | 4·9 (3·1–6·8) | 28 | 3·9 (2·5–5·4) | 25 | 1·6 (1·1–2·2) | 24 |
| Spinal cord injury | 3·2 (2·3–4·2) | 21 | 17·6 (11·9–23·5) | 16 | 74·7 (52·3–99·2) | 10 | 103·2 (74·5–132·7) | 10 | 83·0 (57·6–113·0) | 12 |
| Stroke | 147·5 (109·0–196·8) | 8 | 72·9 (65·0–80·2) | 6 | 1126·1 (1035·5–1218·4) | 1 | 8490·9 (7827·5–9108·6) | 1 | 20 336·1 (17 762·6–22 137·4) | 1 |
| Tension-type headache | 0·0 (0·0–0·0) | NA | 29·7 (4·8–148·1) | 13 | 77·5 (23·3–238·7) | 8 | 75·4 (23·3–224·1) | 12 | 49·4 (12·2–165·8) | 15 |
| Tetanus | 120·5 (51·4–218·6) | 9 | 7·8 (3·5–13·8) | 23 | 7·5 (3·3–12·2) | 26 | 8·2 (3·7–12·8) | 24 | 4·2 (1·5–7·2) | 22 |
| Traumatic brain injury | 3·9 (2·6–5·3) | 20 | 11·8 (8·3–16·0) | 20 | 77·5 (54·2–103·7) | 9 | 176·5 (126·5–236·6) | 8 | 226·3 (160·7–298·5) | 7 |
Rates are provided to one decimal place. Due to rounding, values for some rare conditions (eg, tetanus, rabies, neurocysticercosis, and congenital Zika syndrome) are shown as 0·0, but the actual values are higher than 0·0.
*
Neurological complications related to this condition.