Skip to main content
. 2024 Mar 13;19:2553–2571. doi: 10.2147/IJN.S452824

Figure 3.

Figure 3

Targeting effect and cellular uptake of P-ENVs. (A) Representative IVIS images showing the biodistribution of ENVs and P-ENVs in major organs of ApoE−/− mice. (B) Quantification of the fluorescent intensity of P-ENVs compared with ENVs. n = 3. (C) Representative fluorescence images and (D) quantification of the targeted ability of DiI-labeled ENVs or P-ENVs to injured endothelium in vitro. (red: ENVs or P-ENVs, green: vWF, blue: nuclei). Scale bar = 5 um. n = 5. (E) Representative fluorescence images and (F) quantitative analysis of the uptake of DiI-labeled ENVs or P-ENVs by foam cells (red: ENVs or P-ENVs, green: phalloidin, blue: nuclei). Scale bar = 5 um. n = 4. All data are presented as mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001).