Figure 6.

Biosafety of P-ENVs in ApoE^−/− mice. (A) Quantification of TG, TC, LDL, and HDL after 4-week treatment with PBS, ENVs, or P-ENVs. n = 3. (B) Quantification of RBCs, WBCs, PLTs, and HGB after 4-week various treatments. n =3. (C) Quantification of CREA, BUN, ALT, and AST in various treatment groups. n = 3. (D) Representative H&E staining of heart, liver, spleen, kidney, lung, and brain of ApoE^−/− mice treated with PBS, ENVs, or P-ENVs in vivo. Scale bar = 400 um. All data are presented as mean ± SD.