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. 2024 Mar 15;5(3):218–226. doi: 10.1302/2633-1462.53.BJO-2023-0089.R1

Table III.

Questionnaire for Persons with a Transfemoral Amputation, EuroQol five-dimension questionnaire, and 36-Item Short-Form Health Survey questionnaire assessment over time.

Study Study type Comparisons Findings
Hagberg et al, 200829 Two-year follow-up on osseointegrated prosthesis Q-TFA and SF-36 assessments at baseline and 2 years Q-TFA global score significantly different at 2 years from baseline (p = 0.002). SF-36 general health score no different at 2 years from baseline (p = ns)
Brånemark, et al, 201417 Follow-up on osseointegreated prosthesis for TFA at baseline and 2 years Q-TFA and SF-36 assessments at baseline and 2 years Q-TFA global score significantly different at 2 years from baseline (p < 0.001). SF-36 general health score no different at 2 years from baseline (p = ns)
Hagberg et al, 20148 Two-year follow-up on osseointegrated prosthesis Q-TFA and SF-36 assessments at baseline, and 1 and 2 years Q-TFA global score significantly different from baseline at 1 and 2 years (p < 0.001). SF-36 global significantly different, albeit less sensitive than Q-TFA (p = 0.007). This SF-36 difference represented a minimal important difference which is the smallest difference considered of relevance to a patient.
Brånemark et al, 201913 Follow-up on osseointegreated prosthesis for TFA at baseline, and 2 and 5 years Q-TFA and SF-36 assessments at baseline, and 2 and 5 years Q-TFA global score significantly different at 2 and 5 years from baseline (p < 0.0001). SF-36 general health score no different at 2 and 5 years from baseline (p = ns)
Pospeich et al, 20207 Matched cohort (osseointegrated vs socket prosthesis) for TFA Q-TFA and EQ-5D-3L assessments in osseointegrated vs socket prothesis amputees Statistically signficant differences found between osseointegrated and socket prosthesis on Q-TFA global (p = 0.02); no statistical difference in EQ-5D-3L (p = 0.479)

EQ-5D-3L, EuroQol five-dimension three-level questionnaire; ns, not specified; OPRA, osseointegrated prosthesis for rehabilitation of amputees; Q-TFA, Questionnaire for Persons with a Transfemoral Amputation.