TABLE 3.
Hydrogen bond and pi‐interactions established between the NAD+/HD molecule and the protein residues.
| Interaction a | Residue (chain)/atom | Residue (chain)/atom | Distance (Å) |
|---|---|---|---|
| 1 b | Nicotinamide ring | Isoalloxazine ring | 3.6 |
| 2 b | Nicotinamide ring | Isoalloxazine ring | 3.9 |
| 3 | NAD (D)/N7N | His161 (D)/NE2 | 3.5 |
| 4 | Tyr128 (C)/OH | NAD (D)/N7N | 3.1 |
| 5 | Tyr128 (C)/OH | NAD (D)/O4D | 3.3 |
| 6 | NAD (D)/O2D | FAD (D)/O3′ | 3.7 |
| 7 | NAD (D)/O2A | His194 (D)/NE2 | 2.8 |
a
All interactions in this table correspond to those from Figure 6a.
b
Pi‐interactions are highlighted in bold.