Table 2:
Comparison of cardiac structure and function between SLE patients and reference controls (RC) based on cMRI values.
| Variable | SLE (n=13) | RC (n=22) | p-value |
|---|---|---|---|
| EF (%) | 59 ± 7 | 64 ± 5 | 0.0291 |
| LVM/LVEDV (g/mL) | 0.66 ± 0.08 | 0.62 ± 0.07 | ns |
| LVEDVi (mL/m2) | 72.02 ± 15.4 | 67.40 ± 9.3 | ns |
| LVESVi (mL/m2) | 29.9 ± 10.2 | 24.5 ± 5.6 | ns |
| LVSVi (mL/m2) | 42.56 ± 8.2 | 42.92 ± 5.4 | ns |
| LVMi (g/m2) | 47.31 ± 9.3 | 41.34 ± 4.3 | 0.0454 |
| CI (L/min/m2) | 3 ± 1 | 2.6 ± 0.3 | ns |
| Radial Strain (%) | 29.70 ± 6.2 | 34.37 ± 5.8 | 0.0306 |
| Circumferential Strain (%) | −17.94 ± 2.5 | −19.73 ± 2 | 0.0251 |
| Longitudinal Strain (%) | −18.40 ± 2.2 | −20.10 ± 1.9 | 0.0202 |
| Native T1 (ms) | 1262.5 ± 34.6 | 1258 ± 47 | ns |
| ECV (%) | 28.7 ± 3.1 | 29.4 ± 2.6 | ns |
Results are shown as mean ± S.D. and significance was determined using student t test with or without Welch’s correction as appropriate. EF: ejection fraction, LVM: left ventricular mass; LVEDV: left ventricular end diastolic volume; BSA: body surface area; LVEDVi: left ventricular end diastolic volume index (LVEDV/BSA); LVESVi: left ventricular end systolic volume index (LVESV/BSA); LVSVi: left ventricular systolic volume index (LVSV/BSA); LVMi: left ventricular mass index (LVM/BSA); CI: cardiac index; ECV: extracellular volume. ns represents a p-value > 0.05.