Table 2.

Clinical features of patients infected with Candida spp.

Variable	Patients infected with Candida spp. (n = 36)	Fungal-negative controls (n = 27)	P value
Age
mean ± SD — years	63.03 ± 17.05	56.89 ± 15.48	0.141
18 ~ 60 years	17 (47.22)	18 (66.67)	0.200
> 60 years	19 (52.78)	9 (33.33)
Gender — n (%)
Female	11 (30.56)	8 (29.63)	1.000
Male	25 (69.44)	19 (70.37)
Fever — n (%)	18	8	0.127
Cough — n (%)	12	9	1.000
Sputum production — n (%)	11	9	1.000
Coma	5	6	0.507
Abnormal Chest imaging — n (%)	34	27	0.502
Use of antifungal agents — n (%)	14	7	0.418
White blood cell count
Median (IQR) — ×109/L	11.65 (7.72 ~ 14.95)	10.31 (8.07 ~ 15.05)	0.934
> 10 × 109/L — n (%)	21 (58.33)	15 (55.56)	0.758
< 4 × 109/L — n (%)	1 (2.78)	2 (7.41)
Neutrophil count
Median (IQR) — ×109/L	9.11 (5.92 ~ 11.78)	9.07 (6.15 ~ 14.37)	0.879
> 6.3 × 109/L — n (%)	26 (72.22)	20 (74.07)	1.000
< 1.8 × 109/L — n (%)	0 (0)	0 (0)
Lymphocyte count
Median (IQR) — ×109/L	1.02 (0.71 ~ 1.27)	1.25 (0.67 ~ 1.7)	0.255
> 3.2 × 109/L — n (%)	1 (2.78)	3 (11.11)	0.366
< 1.1 × 109/L — n (%)	21 (58.33)	12 (44.44)
Red blood cell count
Median (IQR) — ×1012/L	2.83 (2.18 ~ 3.94)	2.93 (2.25 ~ 3.37)	0.950
> 5.0 (F) and 5.5 (M) ×1012/L	5 (13.89)	1 (3.7)	0.351
< 4.0 (F) and 4.5 (M) ×1012/L	30 (83.33)	24 (88.89)
Platelet count
Median (IQR) — ×109/L	159.5 (113.5 ~ 228.75)	231 (114 ~ 382)	0.063
> 350 × 109/L — n (%)	2 (5.56)	8 (29.63)	0.038
< 125 × 109/L — n (%)	12 (33.33)	7 (25.93)
Glucose
Median (IQR) — mmol/L	7.15 (5.52 ~ 11.7)	7.93 (5.74 ~ 10.3)	0.972
> 6.1 mmol/L — n (%)	26 (72.22)	19 (70.37)	0.440
< 3.8 mmol/L — n (%)	4 (11.11)	1 (3.7)
Total protein
mean ± SD — g/L	57.61 ± 6.91	59.56 ± 8.07	0.320
> 85 g/L — n (%)	0 (0)	0 (0)	0.796
< 60 g/L — n (%)	23 (63.89)	16 (59.26)
Albumin
mean ± SD — g/L	30.2 ± 5.31	32.8 ± 5.26	0.059
> 53 g/L — n (%)	0 (0)	0 (0)	0.572
< 40 g/L — n (%)	35 (97.22)	25 (92.59)
Globulin
mean ± SD — g/L	27.13 ± 6.6	26.76 ± 5.71	0.812
> 32 g/L — n (%)	8 (22.22)	3 (11.11)	0.498
< 20 g/L — n (%)	5 (13.89)	3 (11.11)