Table 2.
Independent associates of CAN category in FDS2 participants with type 2 diabetes
| Possible CAN | Definite CAN | |
|---|---|---|
| OR (95% CI) | OR (95% CI) | |
| Aboriginal descent | 1.91 (1.01, 3.62) | 1.65 (0.72, 3.78) |
| Diabetes duration (increase of 1 year) | 1.01 (0.98, 1.03) | 1.05 (1.02, 1.08) |
| Body mass index (increase of 1 kg/m2) | 1.02 (0.99, 1.05) | 1.04 (1.005, 1.08) |
| Pulse rate (increase of 1 beat/min) | 1.01 (0.996, 1.03) | 1.04 (1.02, 1.06) |
| On beta-blockers | 1.95 (1.24, 3.09) | 2.86 (1.60, 4.93) |
| On calcium channel blockers | 1.70 (1.15, 2.50) | 2.44 (1.47, 4.04) |
| On antidepressant medication | 1.67 (1.06, 2.64) | 2.81 (1.60, 4.93) |
| Ln [urinary albumin:creatinine ratio (mg/mmol)]a | 1.09 (0.95, 1.24) | 1.29 (1.10, 1.53) |
| Distal symmetrical polyneuropathy | 1.12 (0.79, 1.58) | 1.65 (1.04, 2.61) |
| Prior hospitalisation for heart failure | 2.96 (1.11, 7.92) | 3.46 (1.15, 10.4) |
Multinomial regression was used with no prevalent CAN as the reference. Data are odds ratios (OR) and 95% confidence intervals (CIs). Values are provided for both CAN categories where variables were significant for at least category
aA 2.72-fold increase in urinary albumin:creatinine ratio corresponds to an increased risk of 1 in ln(urinary albumin:creatinine)