Table 2.
Hazard ratio (HR) with 95% confidence interval (CI) for incident lung cancer associated with change of smoking status
| No of cases | 100-person year | Adjusted HR (95% CI) |
Adjusted subHR* (95% CI) |
|
|---|---|---|---|---|
| Sustainer | 225 | 0.75 | Reference | Reference |
| Reducer | 68 | 0.61 | 0.74 (0.56, 0.98) | 0.74 (0.57, 0.97) |
| 20–50% reducer | 39 | 0.67 | 0.84 (0.60, 1.18) | 0.83 (0.59, 1.17) |
| Over 50% reducer | 29 | 0.55 | 0.64 (0.64, 0.95) | 0.64 (0.43, 0.95) |
| Quitter | 176 | 0.73 | 0.78 (0.64, 0.96) | 0.78 (0.64, 0.95) |
Adjusted for age, sex, BMI, residential area, income, regular physical activity, pack-years (Exam 1), ICS within 1 year of Exam 2, severe exacerbation within 1 year of Exam 2, and comorbidities within 1 year of Exam 2.
* Sub-distribution hazard ratios (subHRs) for lung cancer were modelled with mortality as a competing risk.
BMI, body mass index; COPD, chronic obstructive pulmonary disease; ICS, inhaled corticosteroids