Table 2.

Database search protocol representation for this review

Database	Search String
PubMed	(“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign”) AND (“Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD”) AND (“Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”)
Embase	(‘orthodontics’ OR ‘orthodontic appliances’ OR ‘dental braces’ OR ‘aligners’ OR ‘clear aligners’ OR ‘exp orthodontic appliances/‘ OR ‘exp orthodontic aligners/‘) AND (‘temporomandibular joint disorders’ OR ‘temporomandibular joint dysfunction syndrome’ OR ‘exp Temporomandibular Joint Disorders/‘ OR ‘exp Temporomandibular Joint Dysfunction Syndrome/‘)
Web of Science	TS=(“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign”) AND TS=(“Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD”) AND TS=(“Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”)
Scopus	TITLE-ABS-KEY(“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign”) AND TITLE-ABS-KEY(“Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD”) AND TITLE-ABS-KEY(“Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”)
Cochrane Library	(‘orthodontics’ OR ‘orthodontic appliances’ OR ‘dental braces’ OR ‘aligners’ OR ‘clear aligners’ OR ‘MeSH descriptor: [Orthodontic Appliances]’ OR ‘MeSH descriptor: [Orthodontic Aligners]’) AND (‘temporomandibular joint disorders’ OR ‘temporomandibular joint dysfunction syndrome’ OR ‘MeSH descriptor: [Temporomandibular Joint Disorders]’ OR ‘MeSH descriptor: [Temporomandibular Joint Dysfunction Syndrome]’)
CINAHL	((“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign”) AND (“Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD”) AND (“Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”)
PsycINFO	(“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign”) AND (“Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD”) AND (“Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”)
Google Scholar	“Aligner orthodontic treatment” OR “Clear aligner treatment” OR “Invisalign” AND “Masticatory anomalies” OR “Masticatory disorders” OR “Temporomandibular disorders” OR “TMD” AND “Systematic review” OR “Meta-analysis” OR “Review” OR “Clinical study” OR “Observational study” OR “Cohort study” OR “Case-control study” OR “Cross-sectional study” OR “Longitudinal study”