TABLE 2.

Replication of RT mutants in CEM (12D7) cells

Provirus	Amino acid at residuea:				Replicationb at:
	64	65	66	67	34.5°C	37°C	39.5°C
Wild type	K	K	K	D	Yes	Yes	Yes
mt1	A	A	A	A	No	No	No
mt2	K	K	A	A	Yes	Yes	Yes
mt3	R	A	K	D	No	No	No
mt4	A	K	A	A	Yes	Yes	No

^aNumbered with respect to the first residue of the RT protein. 

^bMonitored by measuring RT released from transfected CEM (12D7) cells during a 2-week (39.5 and 37°C) or 3-week (34.5°C) observation period.