TABLE A1.
Kidney Transplant History Details
| ID | Transplant Type | Transplant IS Regimen Details | Primary Kidney Disease | HLA Mismatches | CMV Status | EBV Status | Last Transplant Date to Immunotherapy Start, Yearsa | Squamous Cell Diagnosis | Treatment Details |
|---|---|---|---|---|---|---|---|---|---|
| 01 | DDKT (first 1979) | MMF, prednisone, mTORi | Familial cystinosis | A0B0DR0 (11 antigen matches) | D–/R+ | D+/R+ | 2.8 | Scalp, head and neck | S + RT, CTX |
| 02 | DDKT (first 1991) | Tacrolimus, prednisone | Hypertension | A1B2DR2 | D–/R+ | D+/R+ | 13.5 | Scalp/face, head and neck | S + RT, CTX |
| 03 | LRKT | Tacrolimus, prednisone | HUS/TTP | A0B0DR0 (two haplotype match) | D?/R+ | D?/R+ | 3.5 | Scalp, face, head and neck, extremities | S, CTX |
| 04 | DDKT | Tacrolimus, prednisone | Chronic glomerulitis | A1B2DR0 | D–/R– | D+/R+ | 7.2 | Scalp, face, head and neck | S + RT |
| 05 | LRKT | MMF, prednisone, belatacept | Hypertension | A1B1DR1 (1 haplotype match) | D+/R+ | D+/R+ | 7.2 | Scalp, face, head and neck | S + RT |
| 06 | LUKT | Tacrolimus, prednisone, mTORi | Chronic glomerulitis | A1B2DR1 | D–/R+ | D–/R+ | 4.6 | Scalp, face, head and neck | S + CRT |
| 07 | LUKT (first 1991) | mTORi, prednisone | IgA nephropathy | A1B1DR2 | NA | NA | 21.1 | Scalp, face, head and neck | S + RT, C |
| 08 | DDKT | Cyclosporin, mTORi, MMF | Polycystic kidney disease | A1B1DR0 | D+/R– | D?/R+ | 20.6 | Scalp, face, head and neck | S |
| 09 | LRKT | Tacrolimus, prednisone, azathioprine | Primary FSGS | A1B1DR1 (one haplotype match) | D+/R– | D+/R+ | 9.6 | Scalp, face, head and neck | S + RT |
| 10 | LUKT | Tacrolimus, MMF | Secondary FSGS | A1B2DR2 | D–/R– | D+/R+ | 3.9 | HPV + oropharynx | RT + CTX, S |
| 11 | LRKT | MMF, prednisone, mTORi | Unknown | A1B2DR1 | D+/R– | D+/R+ | 8.5 | Scalp, face, head and neck | S + RT |
| 12 | LUKT (first 1997) | mTORi, prednisone | IgA nephropathy, Alport syndrome | A2B2DR2 | D–/R– | D+/R+ | 4.6 | HPV + oropharynx, lip/face | S + CRT |
Abbreviations: C, chemotherapy; CMV, cytomegalovirus; CRT, concurrent chemoradiation; CTX, cetuximab; D, donor; DDKT, deceased donor kidney transplant; EBV, Epstein-Barr virus; FSGS, focal segmental glomerulosclerosis; HLA, human leukocyte antigen; HUS/TTP, thrombotic thrombocytopenic purpura/hemolytic uremic syndrome; ID, identifier; IgA, immunoglobulin A; IS, immunosuppression; LRKT, living related kidney transplant; LUKT, living unrelated kidney transplant; MMF, mycophenolate mofetil; mTORi, mammalian target of rapamycin inhibitor; NA, not available; R, recipient; RT, radiotherapy; S, surgery.
a
Timing from most recent transplant date in the case of patients who underwent two kidney transplants.