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. 2024 Mar 18;6(3):e1066. doi: 10.1097/CCE.0000000000001066

TABLE 2.

Test Characteristics of Clinical Institute Withdrawal Assessment Alcohol Revised and Lorazepam Milligram Equivalent Restricted Cubic Spline Knots and Odds Ratio Equal to 1

score/dose Knot/Criteria Sensitivity Specificity Positive Predictive Value Negative Predictive Value
Clinical Institute Withdrawal Assessment-Ar Scores
 6 Second knot 0.76 (0.74, 0.77) 0.27 (0.26, 0.28) 0.38 (0.37, 0.40) 0.65 (0.63, 0.67)
 11 Third knot 0.56 (0.55, 0.58) 0.50 (0.49, 0.52) 0.40 (0.39, 0.42) 0.66 (0.64, 0.67)
 15 American Thoracic Society 0.39 (0.37, 0.41) 0.73 (0.71, 0.74) 0.46 (0.44, 0.48) 0.66 (0.65, 0.68)
 16 Fourth knot 0.35 (0.33, 0.37) 0.77 (0.75, 0.78) 0.47 (0.45, 0.49) 0.66 (0.65, 0.67)
 19 American Society of Addiction Medicine 0.24 (0.23, 0.26) 0.86 (0.85, 0.87) 0.51 (0.49, 0.54) 0.65 (0.64, 0.67)
 24 OR = 1 0.12 (0.11, 0.13) 0.95 (0.94, 0.95) 0.58 (0.54, 0.61) 0.64 (0.63, 0.65)
 26 Fifth knot 0.09 (0.08, 0.10) 0.96 (0.96, 0.97) 0.60 (0.55, 0.64) 0.64 (0.63, 0.65)
Lorazepam milligram equivalent
 2.5 mg Second knot 0.58 (0.56, 0.60) 0.53 (0.51, 0.54) 0.42 (0.41, 0.44) 0.68 (0.66, 0.69)
 13 mg Third knot 0.18 (0.17, 0.19) 0.94 (0.94, 0.95) 0.65 (0.62, 0.68) 0.65 (0.65, 0.67)
 15 mg OR = 1 0.16 (0.14, 0.17) 0.96 (0.95, 0.96) 0.68 (0.65, 0.72) 0.65 (0.64, 0.66)

OR = odds ratio.