Figure 3.

Biomarker Concentrations and Systolic Function at Each Study Time Point

Distribution of cardiac troponin (cTn) T and I, amino-terminal pro–B-type natriuretic peptide (NT-proBNP), LVEF, GLS, and relative change in GLS from baseline at baseline (visit 1), after 1 anthracycline cycle (visit 2), at the end of anthracyclines (visit 3), after trastuzumab or radiation therapy (visit 4), and at extended follow-up (visit 5). Horizontal lines represent the different cutoff values; x indicates an outlier (82.3 ng/L). Abbreviations as in Figure 1.