Figure 4.

Troponin Levels After Anthracyclines by Systolic Function at Extended Follow-Up

Distribution of cardiac troponin (cTn) T and I according to whether systolic function was reduced at extended follow-up. Reduced systolic function was defined as a left ventricular ejection decline of ≥10 percentage points to a value between 40% and 49% or a decline in global longitudinal strain of ≥15% from baseline. Horizontal orange and red lines represent sex-specific and sex-neutral upper reference limits, and x indicates an outlier (82.3 ng/L).