Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 24;4(3):336–349. doi: 10.1038/s43587-023-00560-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Mice were treated with m.uPAR-m.28z CAR T cells, h.19-m.28z CAR T cells or UT cells as schematized in Fig. 3a. a, Body weight 24 h before and at various times after cell infusion (n = 12 mice for UT; n = 11 for h.19-m.28z; n = 12 for m.uPAR-m.28z). b, Triglyceride levels 20 d after cell infusion (n = 12 mice for UT; n = 11 for h.19-m.28z; n = 13 for m.uPAR-m.28z). c, Cholesterol levels 20 d after cell infusion (n = 12 for UT and for h.19-m.28z; n = 13 for m.uPAR-m.28z). d, Alanine transaminase (ALT) levels 20 d after cell infusion (sample sizes as in c). e, Aspartate aminotransferase (AST) levels 20 d after cell infusion (n = 12 for UT; n = 11 for h.19-m.28z; n = 13 for m.uPAR-m.28z). f, BUN/creatinine ratio 20 d after cell infusion (sample sizes as in c). g, Creatine kinase (CK) 20 d after cell infusion (n = 12 for UT; n = 9 for h.19-m.28z; n = 11 for m.uPAR-m.28z). h, Hemoglobin levels 20 d after cell infusion (n = 11 for UT; n = 11 for h.19-m.28z; n = 10 for m.uPAR-m.28z). i, Platelet numbers 20 d after cell infusion (n = 11 for UT; n = 11 for h.19-m.28z; n = 10 for m.uPAR-m.28z). j, Lymphocyte numbers 20 d after cell infusion (n = 11 for UT; n = 11 for h.19-m.28z; n = 10 for m.uPAR-m.28z). k, Monocyte numbers 20 d after cell infusion (n = 11 for UT; n = 11 for h.19-m.28z; n = 10 for m.uPAR-m.28z). l, Neutrophil numbers 20 d after cell infusion (n = 11 for UT; n = 10 for h.19-m.28z; n = 10 for m.uPAR-m.28z). m, Eosinophil numbers 20 d after cell infusion (n = 11 for UT; n = 11 for h.19-m.28z; n = 10 for m.uPAR-m.28z). Results are from two independent experiments. Data are the mean ± s.e.m.; P values from two-tailed unpaired Student’s t-test (b–m).

Source data