Table 2.

Echocardiographic parameters

	Healthy controls (n = 17)	FTR (n = 22)	PCPH (n = 20)	P-value
RVGWI, mmHg%	417 ± 73	508 ± 179	646 ± 242†‡	0.003
RVGCW, mmHg%	454 ± 73	687 ± 203†	881 ± 255†‡	< 0.001
RVGWW, mmHg%	10 (6, 17)	91 (53, 140)†	110 (66, 159)†	< 0.001
RVGWE, %	96 ± 3	86 ± 8†	86 ± 10†	< 0.001
TAPSE/PASP, mm/mmHg*	1.34 ± 0.39	0.78 ± 0.35†	0.43 ± 0.32†‡	< 0.001
RV GLS, %	23.7 ± 3.2	16.7 ± 4.0†	15.9 ± 3.4†	< 0.001
RV FWS, %	27.8 ± 3.9	21.8 ± 4.8†	16.5 ± 4.6†‡	< 0.001
RV S’, cm/sec	11.6 ± 1.6	11.2 ± 1.7	11.7 ± 3.5	0.78
TAPSE, mm	27 ± 3	21 ± 4†	16 ± 4†‡	< 0.001
RV FAC, %	46.2 ± 6.2	37.9 ± 6.4†	29.5 ± 11.4†‡	< 0.001
RV Basal Diameter, mm	35 ± 2	51 ± 7†	47 ± 6†	< 0.001
RV Mid Diameter, mm	27 ± 3	42 ± 10†	38 ± 7†	< 0.001
LVEF, %	63 ± 5	59 ± 5†	58 ± 7†	0.021
LV GLS, %	20 ± 2	17 ± 3	18 ± 3	0.051
LV Mass Index, g/m2	77 ± 14	96 ± 24†	71 ± 22‡	< 0.001

Values are mean ± SD or median (interquartile range)

LVEF left ventricular (LV) ejection fraction, LV GLS LV global longitudinal strain, PASP pulmonary artery systolic pressure, RV FAC RV fractional area change, RV FWS RV free wall longitudinal strain, RV GLS RV global longitudinal strain, RVGCW and RVGWW RV global constructive and wasted work, RVGWE and RVGWI RV global work efficiency and index, RV S’ tricuspid annular peak systolic velocity, TAPSE tricuspid annular plane systolic excursion. Other abbreviations as in Table 1

*Available in 44/59 (75%) echocardiographic exams

^†Significantly different versus controls

^†‡Significantly different versus FTR